Pseudomembranous colitis complicated by toxic dilatation of the colon
DOI:
https://doi.org/10.11603/2414-4533.2021.1.12028Keywords:
pseudomembranous colitis, dilatation, toxic megacolon, Clostridium difficile, surgical treatmentAbstract
The aim of the work: demonstration of a clinical case of acute toxic dilation of the colon as a complication of the fulminant form of pseudomembranous colitis.
Pseudomembranous colitis associated with Clostridium difficile is a severe consequence of the use of antibiotics. Toxic megacolon is a rare and extremely severe, irreversible, disabling complication of pseudomembranous colitis, which occurs in 0.4–3 % of cases and leads to fatal outcomes in 35–80 % of cases. This complication require surgical treatment, delay which leads to severe systemic intoxication, exhaustion of the patient and fatal outcomes. Obstructive total/subtotal colectomy is the only recommended surgical intervention that can provide a positive prognosis for the patient’s life. Other surgical interventions are associated with a high risk of reoperations and fatal outcomes.
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