Efficiency of antі-adhesive drugs in planned and urgent enterolise
DOI:
https://doi.org/10.11603/2414-4533.2020.2.10767Keywords:
adhesive disease, Defensal drug, enteroliseAbstract
The aim of the work: to study and compare the results of treatment of patients with adhesive disease of the peritoneum after planned and urgent surgical interventions that underwent adhesolysis and used the Defensal drug. One of the ways to prevent postoperative adhesions is not only the development of modern methods of surgical interventions, intact suture materials and modern implants, but also the search for new methods of preventing postoperative adhesions using anti-adhesive preparations.
Materials and Methods. During the period from 2013 to 2019, 80 patients with adhesive disease were examined and treated, and adhesions were separated, aged 21 to 79 years. Patients were divided into the following groups: 1) the control group included 20 patients who underwent planned surgical and conservative treatment with generally accepted methods with peritoneal joint disease, large incisional hernias; 2) group 2 (20 patients) – planned surgical intervention and separation of adhesions using Defensal drug; 3) group 3 – of 20 patients who underwent acute enterolysis without the use of Defensal with acute commissural small bowel obstruction; 4) group 4 of 20 patients who underwent acute enterolysis with the use of Defensal with acute commissural small bowel obstruction.
Results and Discussion. Good immediate, short-term and long-term results with a follow-up period of up to 6 years were obtained in group 2 after planned surgical interventions and the use of Defensal. However, in group 4 of patients after urgent enterolysis and use of the drug, an improvement in immediate results is visible, however, long-term results practically do not differ from the group 3 of patients. You can achieve better results by using an integrated approach to the prevention and treatment of peritoneal commissural disease, the use of modern and new anti-adhesive drugs.
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