Clinical monitoring of the course and prevention of complications of acute pancreatitis
DOI:
https://doi.org/10.11603/2414-4533.2020.2.10758Keywords:
acute pancreatitis, pancreatic necrosis, procalcitoninAbstract
The aim of the work: to monitor the course of acute pancreatitis in order to prevent complications
Materials and Methods The study was based on a comprehensive clinical and laboratory examination of 226 patients with acute pancreatitis (AP) who were treated at the surgical divisions of Ternopil University Hospital and Ternopil Municipal Hospital No. 2 from 2014 to 2019. Both general laboratory and special laboratory examinations were performed, including the determination of procalcitonin (PCT) by immunochromatographic method. Computed tomography (CT), ultrasound, and magnetic resonance pancreatocholangiography were the main instrumental methods of examination. Software analysis of the obtained data was carried out in the program Statistica Soft 13.0.
Results and Discussion. Early detection of PCT for the verification of infected acute necrotic pancreatitis enabled patients in group II to prevent complications of AP by choosing active surgical treatment. In 86.7 % of patients not operated at the early stages who had high levels of PCT had complications. Increased levels of PCT in patients with severe or critical AP are likely to be indicative of inflammatory infection, so early surgery should be done to prevent complications.
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