Diabetes mellitus type 2 correction, changes in lipids level in connection With ileoduodenoplasty

Authors

  • S. Ye. Podpriatov Kyiv City Clinical Hospital No. 1
  • S. S. Podpriatov Kyiv City Clinical Hospital No. 1
  • N. M. Starchak Scientific and Practical Enterprise ITC Ltd.
  • N. M. Satsiuk Kyiv City Clinical Hospital No. 1
  • V. P. Korchak Kyiv City Clinical Hospital No. 1

DOI:

https://doi.org/10.11603/2414-4533.2020.1.10733

Keywords:

diabetes mellitus type 2, surgical compensation, ileoduodenoplasty, lipids content changes

Abstract

The aim of the work: to estimate lipides changes in connection with ileoduodenoplasty.

Materials and Methods. Content of cholesterol (CH), triglycerides (T), high density lipoproteins (HDLP), low density lipoproteins (LDLP)/ and very low density lipoproteins (VLDLP) was estimated in 45 patients with diabetes mellitus type 2. There were 20 men, 25 women, mean (M±m) age (27.4±9.5) years. Body mass index was from 23.4 to 61.4 kg/cm2.

For glycaemia correction pill medication use 12 patients, insulin injection 18, first revealed diabetes or insulin resistance with poorly corrected hypertension and cardiac insufficiency of 2 stage have 15 patients. Mean (M±Ϭ) diabetic duration was (15.1±7.7 years.

Results and Discussion. Quick and substantial lowering CH content was found in all cases, what, probably, is connected to achieving diabetes mellitus compensation.

Stability of the CH content at the normal level in long-term follow up may be the main factor in substantial diabetes compensation.

Controversial changes levels of TG, HDLP, LDLP, VLDLP suggested absence their direct connection to glucose metabolism.

References

Podpriatov, S.Ye., Podpriatov, S.S., & Starchak, N.M. (2019). Korektsiia tsukrovoho diabetu II typu, zminy c-peptydemii ta insulinemii pislia vykonannia ileoduodenoplastyky [Type 2 diabetes mellitus, changes in c-peptidemia and insulinemia after ileoduodenoplasty]. Suchasni medychni tekhnolohii – Modern Medical Technologies, 3, 18-25 [in Ukrainian].

Martínez-Mardones, F., Fernandez-Llimos, F., Benrimoj, S.I., Ahumada-Canale, A., Plaza-Plaza, J.C.S., Tonin, F., & Garcia-Cardenas, V. Systematic review and meta-analysis of medication reviews conducted by pharmacists on cardiovascular diseases risk factors in ambulatory care. J. Am. Heart Assoc., 8 (22). e013627. doi: 10.1161/JAHA.119.013627. Epub 2019 Nov 12. DOI: https://doi.org/10.1161/JAHA.119.013627

Ojo, O., Weldon, S.M., Thompson, T., Crockett, R., & Wang, X.H. (2019). The effect of diabetes-specific enteral nutrition formula on cardiometabolic parameters in patients with type 2 diabetes: A systematic review and meta-analysis of randomised controlled trials. Nutrients, 11 (8). pii: E1905. doi: 10.3390/nu11081905. DOI: https://doi.org/10.3390/nu11081905

Lemmers, R.F.H., van Hoek, M., Lieverse, A.G., Verhoeven, A.J.M., Sijbrands, E.J.G., & Mulder, M.T. The anti-inflammatory function of high-density lipoprotein in type II diabetes: A systematic review. J. Clin. Lipidol., 11 (3), 712-724.e5. doi: 10.1016/j.jacl.2017.03.013. Epub 2017 Mar 31. DOI: https://doi.org/10.1016/j.jacl.2017.03.013

Cao, Y., Yan, L., Guo, N., Yu, N., Wang, Y., Cao, X., Yang, S., & Lv, F. (2019). Non-high-density lipoprotein cholesterol and risk of cardiovascular disease in the general population and patients with type 2 diabetes: A systematic review and meta-analysis. Diabetes Res. Clin. Pract., 147, 1-8. doi: 10.1016/j.diabres.2018.11.002. Epub 2018 Nov 16. DOI: https://doi.org/10.1016/j.diabres.2018.11.002

Qian, F., Korat, A.A., Malik, V., & Hu, F.B. (2016). Metabolic effects of monounsaturated fatty acid-enriched diets compared with carbohydrate or polyunsaturated fatty acid-enriched diets in patients with type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials. Diabetes Care, 39 (8), 1448-1457. doi: 10.2337/dc16-0513. DOI: https://doi.org/10.2337/dc16-0513

Qi, L, Guo, Y., Liu, C.Q., Huang, Z.P., Sheng, Y., & Zou, D.J. (2017). Effects of bariatric surgery on glycemic and lipid metabolism, surgical complication and quality of life in adolescents with obesity: a systematic review and meta-analysis. Surg. Obes. Relat. Dis., 13 (12), 2037-2055. doi: 10.1016/j.soard.2017.09.516. Epub 2017 Sep 19 DOI: https://doi.org/10.1016/j.soard.2017.09.516

Huang, Z.P., Guo, Y., Liu, C.Q., Qi, L., Zou, D.J., & Zhou, W.P. (2018). The effect of metabolic surgery on nonobese patients (BMI<30 kg/m2) with type 2 diabetes: a systematic review. Surg. Obes. Relat. Dis., 14 (6), 810-820. doi: 10.1016/j.soard.2018.02.013. Epub 2018 Feb 15. DOI: https://doi.org/10.1016/j.soard.2018.02.013

Ji, G., Li, P., Li, W., Sun, X., Yu, Z., Li, R., Zhu, L., & Zhu, S. The effect of bariatric surgery on Asian patients with type 2 diabetes mellitus and body mass index < 30 kg/m2: A systematic review and meta-analysis. Obes. Surg., 29 (8), 2492-2502. doi: 10.1007/s11695-019-03861-0. DOI: https://doi.org/10.1007/s11695-019-03861-0

de La Harpe, R., Rüeger, S., Kutalik, Z., Ballabeni, P., Suter, M., Vionnet, N., Laferrère, B., & Pralong, F. (2019). Weight loss directly influences intermediate-term remission of diabetes mellitus after bariatric surgery: A retrospective case-control study. Obes. Surg., 21. doi: 10.1007/s11695-019-04283-8. DOI: https://doi.org/10.1007/s11695-019-04283-8

Published

2020-01-16

How to Cite

Podpriatov, S. Y., Podpriatov, S. S., Starchak, N. M., Satsiuk, N. M., & Korchak, V. P. (2020). Diabetes mellitus type 2 correction, changes in lipids level in connection With ileoduodenoplasty. Hospital Surgery. Journal Named by L.Ya. Kovalchuk, (1), 28–33. https://doi.org/10.11603/2414-4533.2020.1.10733

Issue

Section

ORIGINAL INVESTIGATIONS