Staged surgical treatment of cholangiogenic abscesses of the liver

Authors

  • V. V. Boyko V. Zaitsev Institute of General and Emergency Surgery, Kharkiv¬ Kharkiv National Medical University
  • V. M. Lykhman V. Zaitsev Institute of General and Emergency Surgery, Kharkiv¬
  • D. A. Miroshnichenko Kharkiv National Medical University
  • A. A. Merkulov V. Zaitsev Institute of General and Emergency Surgery, Kharkiv¬
  • S. V. Tkach V. Zaitsev Institute of General and Emergency Surgery, Kharkiv¬
  • A. N. Shevchenko V. Zaitsev Institute of General and Emergency Surgery, Kharkiv
  • A. V. Moskalenko Kharkiv National Medical University
  • I. V. Volchenko Kharkiv National Medical University

DOI:

https://doi.org/10.11603/2414-4533.2020.1.10731

Keywords:

cholangiogenic liver abscess, ultrasound-controlled drainage

Abstract

The aim of the work: to improve the results of treatment of patients with cholangiogenic liver abscesses by means of staged treatment methods using minimally invasive interventions.

Materials and Methods. 82 patients with cholangiogenic liver abscesses aged 21 to 80 years who underwent 130 operations were examined and treated. The main group consisted of 40 (48.4 %) patients who underwent ultrasound-controlled drainage of abscess cavities (stage I), followed by removal of the source of cholangiogenic abscesses (stage II). The comparison group consisted of 42 (51.6 %) patients who underwent rehabilitation and drainage only with laparotomy access.

Results and Discussion. Minimally invasive methods of surgical treatment included ultrasound-controlled drainage with simultaneous rehabilitation of abscess cavities. The dimensions of the cavities averaged (150±23.3) cm³. One drainage was used to drain the liver abscess with a diameter of up to 10.0 cm. When the diameter of the abscess was more than 5.0 cm, drainage was carried out by two single-lumen tubes followed by suction-flow washing of the abscess cavity. Monitoring the standing of the drainage and reducing the cavity of abscesses was carried out on 3, 7, 14 days after setting. The drainage tube was removed after the disappearance of the cavity according to ultrasound and control fistulography, which coincided with the normalization of the general condition and body temperature, the disappearance of signs of purulent intoxication. Duration of drainage averaged from 7 to 30 days (an average of 15.2). The proposed treatment method is not very traumatic, the ability to control the effectiveness of the treatment, and most importantly – positive results in 87 % of patients. Second stage in 38 (95 %) was performed laparoscopic cholecystectomy of technical features. The optimal duration of stage II was considered (13±3) days after extraction of the drainage. In the diagnosis and treatment of cholangiogenic liver abscesses, it is necessary to use puncture ultrasound-controlled drainage methods. The stage-by-stage treatment of cholangiogenic liver abscesses with rehabilitation of the abscess cavity made it possible to reduce the incidence of sepsis from 9.5 to 2.5 %, reduce postoperative mortality in extremely severe patients to 2.4 %, and develop complications by 7.3 %.

References

Akhaladze, G.G. (2012). Klyuchevye voprosy khirurgicheskogo lecheniya abstsessov pecheni [Key issues for the surgical treatment of liver abscesses]. Annaly khirurgicheskoy gepatologii – Annals of Surgical Hepatology, 17 (1), 53-58 [in Russian].

Efimov, D.S. (2015). Opyt lecheniya abstsessov pecheni v usloviyakh bolnitsy skoroy [Experience in the treatment of liver abscesses in an emergency hospital]. Kharkіvska khіrurhіchna shkola – Kharkiv Surgical School, 6 (75), 172-177 [in Russian].

Ovchinnikov, V.A., Malov, A.A., & Akulenko, S.V. (2013). Sovremennaya taktika v lechenii bakterialnykh abstsessov pecheni [Modern tactics in the treatment of bacterial abscesses of the liver]. Meditsinskiy almanakh – Medical Almanakh, 5 (28), 99-102 [in Russian].

Pashchina, S.N., Blagitko, E.M., & Bespalov, A.A. (2014). Abstsessy pecheni: vybor metoda lecheniya [Liver abscesses: the choice of treatment]. Meditsina i obrazovanie v Sibiri – Medicine and Education in Siberia, 14, 54-56 [in Russian].

Alvarez Perez, J., Gonzalez, J., & Baldonedo, R. (2001). Clinical course, treatment, and multivariate analysis of risk factors for pyogenic liver abscess. Am. J. of Surg., 181 (2), 177-186. DOI: https://doi.org/10.1016/S0002-9610(00)00564-X

Dellinger, R.P., Levy, M.M., & Rhodes, A (2013). Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock. Intensive Care Med., 41 (2), 580-637. DOI: https://doi.org/10.1097/CCM.0b013e31827e83af

O’Farrell, N., Collins, C.G., & McEntee, G.P. (2010). Pyogenic liver abscesses: diminished role for operative treatment. Surgeon, 8 (4), 192-196. DOI: https://doi.org/10.1016/j.surge.2010.01.001

Sugiama, M., & Atomi, Y. (2002). Pyogenic hepatic abscess with biliary communication. Am. J. Surg., 183, 2. DOI: https://doi.org/10.1016/S0002-9610(01)00869-8

Published

2020-01-16

How to Cite

Boyko, V. V., Lykhman, V. M., Miroshnichenko, D. A., Merkulov, A. A., Tkach, S. V., Shevchenko, A. N., … Volchenko, I. V. (2020). Staged surgical treatment of cholangiogenic abscesses of the liver. Hospital Surgery. Journal Named by L.Ya. Kovalchuk, (1), 20–23. https://doi.org/10.11603/2414-4533.2020.1.10731

Issue

Section

ORIGINAL INVESTIGATIONS