Comparative assessment of different methods of wound defects closure in patients with diabetic foot syndrome

Authors

  • I. Ya. Dzyubanovsky I. Horbachevsky Ternopil National Medical University
  • R. M. Antoshchuk Volyn Regional Hospital of War Veterans
  • A. M. Prodan I. Horbachevsky Ternopil National Medical University

DOI:

https://doi.org/10.11603/2414-4533.2019.3.10547

Keywords:

diabetes mellitus, diabetic foot syndrome, dermal equivalent, platelet-rich plasma

Abstract

The aim of the work: to improve the results of surgical treatment of patients with diabetic foot syndrome using modern methods of wound defects closure.

Materials and Methods. The results of complex examination and treatment of 67 patients with diabetic foot syndrome were performed. The observed patients were divided into: comparison group – 31 (46.27 %) patients, who underwent “classic” autodermoplasty and the main group – 36 (53.73 %) patients. Among the last in 17 (47.22 %) the wound defect was closed with the help of the dermal equivalent, and in 19 (52.78 %) was used the PRP technique. In accordance with the clinical forms of the diabetic foot syndrome, the neuropathic form was indicated in 30 (44.78 %) patients and the neuro-ischemic form in 37 (55.22 %) patients. Based on the results obtained using various methods of defect closure, the area and rate of wound healing were calculated.

Results and Discussion. Analyzing the results of the use of the equivalent of the dermis, the following was established: for 20 days of treatment the area of ​​the wound is 1.76 times smaller than the area of ​​the wound in patients without the use of the equivalent of the dermis; the wound healing rate is 1.41 higher. When using the PRP membrane, it is found that by the 20th day of treatment the wound area is 2.25 times smaller than the wound area in patients without using the PRP membrane, and the wound healing rate is 1.45 higher. The use of cell-tissue technologies and platelet-rich membrane with growth factors in topical wound defect treatment allows healing and improves treatment outcomes by accelerating the time of epithelialization over conventional therapy.

References

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Published

2019-11-04

How to Cite

Dzyubanovsky, I. Y., Antoshchuk, R. M., & Prodan, A. M. (2019). Comparative assessment of different methods of wound defects closure in patients with diabetic foot syndrome. Hospital Surgery. Journal Named by L.Ya. Kovalchuk, (3), 57–61. https://doi.org/10.11603/2414-4533.2019.3.10547

Issue

No. 3 (2019)

Section

EXPERIENCE OF WORK

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