Is there alternative to radical cystectomy in treating patients with muscle-invasive low-grade bladder cancer?

Authors

  • P. G. Yakovlev O. Bohomolets National Medical University, Kyiv

DOI:

https://doi.org/10.11603/2414-4533.2019.2.10415

Keywords:

muscle-invasive bladder cancer, radical cystectomy, organ sparing surgery, trimodality treatment, overall survival

Abstract

The aim of the work: to assess the prevalence of bladder sparing surgeries (BSS) combined with perioperative treatment as alternative to radical cystectomy (RCE) in managing patients with urothelial high-grade muscle-invasive bladder cancer (HGMIBC), and assess their effect on overall survival.

Materials and Methods. Retrospectively analyzed data of 309 patients with urothelial HGMIBC: clinical stage of cancer; surgery performed: RCE, partial cystectomy (PCE), transurethral resection of bladder (TURB); use of radio- or chemotherapy after BSS; survival data.

Results and Discussion. 109 (35.3%) RCE and 200 (64.7%) BSS were performed. The overall survival after 5 years post treatment for stages II, III and IV after RCE was 43 %, 37 % and 10 %, after TURB – 58 %, 27 %, and 19 %, and after PCE – 53 %, 42 % and 40 %.
Ker

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Published

2019-09-10

How to Cite

Yakovlev , P. G. (2019). Is there alternative to radical cystectomy in treating patients with muscle-invasive low-grade bladder cancer?. Hospital Surgery. Journal Named by L.Ya. Kovalchuk, (2), 28–33. https://doi.org/10.11603/2414-4533.2019.2.10415

Issue

No. 2 (2019)

Section

ORIGINAL INVESTIGATIONS

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