ASSORTMENT RESEARCH OF SLEEPING AND SEDATIVE MEDICINES CONTAINING COMPONENTS OF PLANT ORIGIN IN UKRAINE
DOI:
https://doi.org/10.11603/2312-0967.2022.4.13738Keywords:
sleeping and sedative medicines, components of plant origin, assortmentAbstract
The aim of the work. The assortment analysis of sleeping and sedative medicines containing components of plant origin in Ukraine for determination the prospects and feasibility of developing new effective domestic drugs.
Materials and Methods. The objects of the study were sleeping and sedative medicines containing components of plant origin according to the Compendium and the State Register of Medicines of Ukraine. A marketing study of sleeping and sedative medicines containing components of plant origin was conducted using statistical, marketing and graphic analysis methods.
Results and Discussion. The assortment research of sleeping and sedative medicines consisting of components of plant origin was conducted according to anatomical-therapeutic-chemical classification, country and manufacturing company, composition and type of dosage form, the macrocontour of the studied segment of the Ukrainian pharmaceutical market is formed. It was established that on January 01, 2023 57 trade names were registered on the market of Ukraine, they belong to the group N05CM “Sleeping and sedative drugs”, it was determined that 73.7 % of the assortment is domestic, and 26.3 % of foreign production. The most common dosage form is capsules (26.3 %), coated tablets (24.5 %) and tinctures (12.3 %). It was determined that combined preparations of natural origin dominate the assortment of drugs – 55.4 %, 68.4 % of preparations contain valerian rhizomes with roots in the form of tinctures, dry, thick or liquid extracts.
Conclusions. The necessity to search and develop new medicines with promising types of medicinal plants with sleeping and sedative effects has been proven.
References
Booth J, Connelly L, Lawrence M. Evidence of perceived psychosocial stress as a risk factor for stroke in adults: a meta-analysis. BMC Neurol. 2015;15: 233.
Kotlega D, Golab-Janowska M, Masztalewicz M. The emotional stress and risk of ischemic stroke. Neurol. Neurochir. Pol. 2016;50(4): 265-70.
Ding WY, Gupta D. Physician Estimation of Thrombotic and Bleeding Risks in Atrial Fibrillation: Letєs Talk about Sex. Sanadian J Cardiol. 2019;35(2): 145-6. doi: 10.1016/j.cjca.2018.12.011.
Henderson DF, Qvick TL. A century of Stress: Stress Theories and Preventive Management in a Global Context. Organizational Psychology. 2015;5(3): 10-25.
Kivimaki M., Nyberg S.T. Long working hour as a risk factor for atrial fibrillation: a multi-cohort study. Eur Heart J. 2017;38(34): 2621-8. DOI: 10.1093/eurheartj/ehx324.
American Psychological Association. Stress in America: The State of Our Nation. Stress in America TM Survey, November 1, 2017.
Lagraauw HM. Acute and chronic psychological stress as risk factors for cardiovascular disease: insights gained from epidemiological, clinical and experimental studies. Brain Behavior Immunity. 2015;50: 18-30. DOI: 10.1016/j.bbi.2015.08.007.
Kovalenko VM. Ed. Stress and cardiovascular diseases and conditions of martial law. Kyiv, National Scientific Center "Institute of Cardiology, Clinical and Regenerative Medicine named after Academician M. D. Strazhesk of NAMS of Ukraine: 2022. Ukrainian.
Kovalenko VM, Kornatskyi VM Eds. Stress and diseases of the circulatory system: manual. [Стрес і хвороби системи кровообігу : посібник] Kyiv; 2015. Ukrainian.
Koval SM, Snihurska IO. [Stress-induced arterial hypertension and wartime arterial hypertension are formidable challenges for modern Ukraine]. Arteryalnaya gipertenzyia. 2015;5: 13-18. Ukrainian.
Kornatskyi VM, Mykhalchuk VM, Diachenko LO. [The influence of stress on the development and course of diseases]. Svit medytsyny ta biol. 2017;1(59): 194-201. Ukrainian.
Savelieva OV, Vladymyrova IM. [Analysis of the nomenclature of sedative and hypnotic drugs in Ukraine]. Farmatsevtychnyi chasopys. 2015;3: 40-3. Ukrainian.
Hudzenko AV, Anzina KM. [Analysis of the market of multi-component medicinal products of plant origin, showing CNS tonic activity]. Zb. nauk. prats spivrobit. NMAPO imeni P. L. Shupyka. 2016;26: 162-8. Ukrainian.
Yakovenko OV, Ruban OA, Hrynenko VV. The marketing research of drugs for prevention and treatment of stress conditions at the pharmaceutical market of Ukraine. Visnyk farmatsii. 2018;4(96): 52-6. https://doi.org/10.24959/nphj 18.2229. Ukrainian.
Hladysheva SA, Al Nasir Eiiad, Luts VV. [Analysis of the state and prospects for the development of sedative drugs on the modern pharmaceutical market of Ukraine]. Aktualni pytannia farmatsevtychnoi i medychnoi nauky ta praktyky. 2021; 14,1(35): 114-9. https://doi.org/10.14739/2409-2932.2021.1.226869. Ukrainian.
Compendium of medicines. Available from: https://compendium.com.ua.
State register of medicines. Available from: http://www.drlz.com.ua.
Petkov VA. [Psychological features of the influence of stress on the general development of a child]. Osvita ta rozvytok obdarovanoi osobystosti. 2015;6(37): 33-6. Ukrainian.
Anopriienko OV. Posttraumatic stress disorder in adolescent children from the ATO zone. Collection of abstracts of the 3rd All-Ukrainian scientific and practical conference with international participation "Actual issues and prospects for the development of medical care and social services for adolescents and young people based on the principles of a "friendly approach" in Ukraine." Kyiv, 2016. Ukrainian.
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