SOME FEATURES OF THE HUMAN MICROBIOME
DOI:
https://doi.org/10.11603/1681-2727.2024.4.15005Keywords:
microbiome, symbiosis, macroorganism, microorganismAbstract
The article provides examples of using modern methods of human microbiome research, for example transcriptomics, metagenomics, and metabiomics, which are based on decoding the genomes of microorganisms, which make it possible to assess the species composition of the microbiota of the human body certain biotope without isolating pure cultures.
A short historical overview of the human microbiome study and the contribution of national and foreign researchers to the development of knowledge about the microbiome is given.
The functions performed by the human microbiome in the vital activity of the macroorganism and their influence on the efficiency of the work of numerous macroorganism organs and systems of the organs, in particular the immune system, are thoroughly described.
The role of the microbial well-being of the future mother’s body in the formation of the neonatal microbiota and its ability to perform key functions in the baby’s body is shown.
The biosociological significance of microbial symbionts and their connection with the socio-psychological «climate»of human were considered.
The review emphasizes the importance of the stability of the composition of the human microbiome and the factors that can affect it, thereby causing negative effects on the body as a whole. Some features of the microbial landscape of the most important human biotopes are characterized.
The review points out the importance of a stable composition of the human microbiome and the factors that can affect it, thereby causing negative effects on the body. Some features of the microbial landscape of the most important human biotopes are characterized.
This work expands the understanding by specialists of all branches of medicine the knowledge about the composition of the human microbiome, the role of its microorganisms in the physiological functioning the human body and their importance in the formation of pathological states of various localization, indicates the possibility of maintaining the stability of the microbiome in different biotopes and the possibility of their correction by improving the health of the human microbiome.
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