Bone repair of the jaws under the influence of a mixture of bioactive glass and autologous bone marrow
DOI:
https://doi.org/10.11603/2311-9624.2018.1.8159Keywords:
marrow, osteoplastic material, bioactive glass, bone cavities, cyst.Abstract
Summary. Operation on removing odontogenic jaw cysts is one of the most common surgical interventions. Patients with radicular cysts of the maxillary bones make up about 6 % in the overall structure of dental morbidity. After the removal of cysts the bone cavities are formed, the healing of which is accompanied by frequent suppuration and is long-lasting. To speed up the healing of bone cavity using various grafts made of native or synthetic bone.
The aim of the study – to improve the efficacy of treatment for odontogenic cysts, we decided to combine autologous bone marrow with an artificial bone substitute, creating a mixture that, by replacing bone defects with it, would optimize reparative processes and thus restore the anatomical and functional properties of the dento-facial system.
Materials and Methods. 60 patients aged 18–65 years who were operated on the basis of radicular jaw cysts were examined. The patients were on inpatient treatment at the Department of Maxillofacial Surgery of Ivano-Frankivsk Regional Clinical Hospital. The diagnosis of the disease was verified on the basis of the data of the X-ray examination. The radiographic dimensions of the cysts were within 1.5–3.5 cm. Depending on the type of material used to substitute postoperative bone cavities, patients were divided into III groups: I – in 20 patients restoration was made a blood clot; II – in 20 patients postoperative bone defects were replaced with bioactive glass, and ІІІ – in 20 patients postoperative bone defects were replaced with a mixture of autologous bone marrow and bioactive glass.
Conclusions. The developed composite material of bioactive glass with the addition of an autologous bone marrow is an inductor and a source of osteogenesis, which allows to recommend it as a method of choice in the treatment of patients with bone defects of the jaws that are formed after the removal of odontogenic cysts. Thus, the prospectivity and importance of the use of bioplastic material in the clinical practice of marrow bioactive mixture in clinical practice will significantly expand the possibilities of modern reconstructive and restorative maxillofacial surgery.
References
Voitovich A., Diiakevich M., Zhytsik V. Auhementatsiia kistky v implantolohii: klityny ta faktory z krovi ta kistkovoho mozku// 4 Skhidnoievropeiska konferentsiia z problem stomatolohii. - 2009. – S. 26-27.
Malanchuk V., Chumachenko A., Tsylenko O. Zastosuvannia kistkovozaminnykh materialiv pry zamishchenni defektiv shchelep // 4 Skhidnoievropeiska konferentsiia z problem stomatolohii. - 2009. – S. 18-19.
Bernadskyi Yu.I. Osnovy shchelepno-lytsevoi khirurhii i khirurhichnoi stomatolohii. – Kyiv: Spalakh, 2003. – S. 173-384.
Vares Ya.E. Dynamika vidnovlennia shyryny alveoliarnykh vidrostkiv pislia provedennia kistektomii shchelep //Novyny stomatolohii. – 2001. – №3(28). – S.47-49.
El Basha Salekh. Osteometriia yak ob¢iektyvnyi metod doslidzhennia konsolidatsii zlamiv nyzhnoi shchelepy //Praktychna medytsyna. – 1998. – №5-6. – S.147-149.
Korniienko H.I., Hot I.M. Viddaleni rezultaty khirurhichnoho likuvannia radykuliarnoi kisty z vykorystanniam kompozytsii MK-9 //Aktualni problemy stomatolohii. – Lviv, 1998. – S.74.
Lomnytskyi I.Ia. Zamishchennia defektiv shchelep demineralizovanymy allotransplantatamy iz zadanymy vlastyvostiamy. – Lviv: Haldent, 1999. – 84s.
Piuryk V.P. Transplantatsiia kistkovoho mozku pry likuvanni parodontytu i kistkovykh porushen shchelep. Avtoref. dys. d-ra med. nauk. Ivano-Frankivskyi med. in-t. – K., 1993. – 36s.
Tymofeev A.A. //Rukovodstvo po cheliustno-lytsevoi khyrurhyy y khyrurhycheskoi stomatolohyy: OOO “Chervona Ruta-Turs”, – 2002. – S.318-323.
Gervasio A. M., Silva D.A., Takemoti E.A. et al. Levels of GM-CSF, IL-3, IL-6 in fluid and tissue from human radicular cysts //Journal of Dental Research (NLM-Medline) – 2002. – Jan. – P.64-68.
