FEATURES OF ENDOMETRIUM BLOOD SUPPLY IN PATIENTS WITH INFERTILITY DUE TO REDUCED OVARIAN RESERVE
DOI:
https://doi.org/10.11603/24116-4944.2018.2.9372Keywords:
velocimetry, endometrium, infertility, ovarian reserveAbstract
The aim of the study – to investigate the state of the endometrial blood flow in women with infertility due to a reduced ovarian reserve and unsuccessful IVF attempts.
Materials and Methods. We examined 120 reproductive age patients with infertility due to reduced ovarian reserve and unsuccessful IVF attempts. All women were divided into two groups: basic (n = 60) and comparison (n = 60). Each group had two subgroups: subgroups of patients with a reduced ovarian reserve due to ovarian surgery in the past and subgroups with a genetically reduced ovarian reserve. Two-dimensional and three-dimensional echography and three-dimensional energy Dopplerography were used to determine the state of the endometrium. The study was conducted on the 7th day of the menstrual cycle preceding the cryobriotransfer.
Results and Discussion. The author did not record the difference between subgroups in terms of the volume of the endometrium (2.21±0.03); (2.23±0.04); (2.28±0.06) and (2.17±0.06) сm3, p>0.05) and the vascularization index (12.23±1.19); (14.09±1.31); (11.84±1.54) and (12.56±1.43) %, p>0.05), while the blood flow index was less than that indicated in the literature for gynecologically healthy women. The determination of vascularization-flow index showed its almost three-fold decrease in comparison with the data of other authors for healthy women. Moreover, this index was significantly (p<0.05) lower in patients with a genetically reduced ovarian reserve (0.82±0.03) and (0.87±0.03) than in women whose ovarian reserve was reduced due to surgical interventions (1.06±0.03) and (1.11±0.04).
Conclusion. Women with infertility due to decreased ovarian reserve have significantly worse blood supply of the endometrium than healthy women, but in patients with operated ovaries it is better compared to women with a genetically determined reduced ovarian reserve.
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