LIPID PEROXIDATION, AS A RESULT OF OXIDATIVE STRESS IN WOMEN WITH CHANGES OF REPRODUCTIVE HEALTH ON THE BACKGROUND OF SOMATOFORM DISEASES WITH VIOLATIONS OF AUTONOMIC HOMEOSTASIS
DOI:
https://doi.org/10.11603/24116-4944.2017.2.8095Keywords:
violations of autonomic homeostasis, changes in reproductive health, lipid peroxidation, oxidative stress.Abstract
The aim of the study – to learn the the content of phospholipids and neutral lipids of blood cells in women of childbearing age with changes in reproductive health and disorders of autonomic homeostasis.
Materials and Methods. We examined 360 women with changes in reproductive health that had an artificial abortion, infertility or uterine leiomyoma and such violation of autonomic homeostasis as autonomic dysfunction syndrome, somatoform dysfunction of autonomic nervous system by hypertonic, hypotonic and cardiac type.
Results and Discussion. We found activation of lipid peroxiadtion in women with changes of reproductive health and violations of the autonomic homeostasis. Different types of autonomic homeostasis violations in combination with changes in reproductive health causes different types of lipid peroxidation activation. According to our data most intensive lipid peroxidation was found in women with all studied violations of autonomic homeostasis, who had an artificial abortion.
Conclusions. Oxidative stress is an important pathogenetic mechanism in development of changes in reproductive health in women with somatoform diseases and violations of autonomic homeostasis.
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