MODERN ASPECTS OF DIAGNOSIS OF PATHOLOGICAL PROCESSES OF CERVIX IN WOMEN WITH ENDOCRINE INFERTILITY

Authors

  • A. V. Boichuk ДВНЗ «Тернопільський державний медичний університет імені І. Я. Горбачевського МОЗ України»
  • V. S. Shadrina ДВНЗ «Тернопільський державний медичний університет імені І. Я. Горбачевського МОЗ України»
  • V. V. Sopel ДВНЗ «Тернопільський державний медичний університет імені І. Я. Горбачевського МОЗ України»
  • V. O. Khudobiak Центр планування сім’ї та репродукції людини пологового будинку Рівненської міської ради

DOI:

https://doi.org/10.11603/24116-4944.2017.2.8042

Keywords:

cervical diseases, viral affection, endocrine infertility.

Abstract

The aim of the study – to investigate the hormonal changes in women with cervical pathology.

Materials and Methods. In a study we used clinical, biochemical, histological and instrumental methods of examination. We studied the medical history, the results of CVU, cytology, Pap-test, colposcopy, data of histological examination, ultrasonography, basal temperature, the results of the PCR diagnostic of STI and HPV, hormonal tests.

Results and Discussion. 105 women aged from 18 to 42 years were under the supervision from 2011 to 2015, the average age was 25.92 ± 0.61 years. The criteria for including patients in the study were pathological processes of cervix and menstrual disorders. Patients were divided into 2 groups, 40 women were in each group. The first group consisted of women with cervical background processes (ectopy, ectropion, cervicitis), the second group – women with precancerous diseases of the cervix (dysplasia, leukoplakia). The control group included 25 healthy women from 18 to 38 years, average age 21.44 ± 0.38 years. Analyzing the levels of hormones in women with endocrine disorders and pathological processes of cervix it was found the impact of hyperandrogenism and luteal phase deficiency into proliferative processes of cervix. These women have a high percentage of hyperandrogenism (46.25 %), the luteal phase deficiency (32.5 %), rarely – hiperestrohenemiya (11.25 %).

Conclusions. We found that among the etiological factors of cervical diseases a leading place belongs to viral associations, mostly of herpesvirus family (CMV – 43.75 %, herpes simplex virus type ½ – 41.25 %, Epstein-Barr virus – 27.5 %) and human papilloma virus – 40.0 % and also to sexually transmitted infections (Ureaplasma spp. – 62.5 %, Chlamydia trachomatis – 11.25 %, Mycoplasma genitalium – 3.75 %).

Author Biography

A. V. Boichuk, ДВНЗ «Тернопільський державний медичний університет імені І. Я. Горбачевського МОЗ України»

 

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Published

2017-10-04

How to Cite

Boichuk, A. V., Shadrina, V. S., Sopel, V. V., & Khudobiak, V. O. (2017). MODERN ASPECTS OF DIAGNOSIS OF PATHOLOGICAL PROCESSES OF CERVIX IN WOMEN WITH ENDOCRINE INFERTILITY. Actual Problems of Pediatrics, Obstetrics and Gynecology, (2). https://doi.org/10.11603/24116-4944.2017.2.8042

Issue

No. 2 (2017)

Section

OBSTETRICS AND GYNECOLOGY

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