TREATMENT OF CHRONIC ENDOMETRITIS IN THE LATE REPRODUCTIVE AND PREMENOPAUSAL PERIOD
DOI:
https://doi.org/10.11603/24116-4944.2017.2.7803Keywords:
chronic endometritis, late reproductive age, premenopause, ozone therapy.Abstract
The aim of the study – to evaluate the effectiveness of intrauterine ozone therapy in the complex treatment of chronic endometritis.
Materials and Methods. 204 women aged 35–54 years with chronic endometritis were selected. Depending on the method of treatment of this pathology, the patients were divided into two groups: in the first group (n = 91) ozone therapy was used in the treatment, in the second group (n = 113) – the traditional scheme. The anamnesis of the disease, the results of general clinical and hysteroscopic examinations, data of morphological and immunohistochemical studies, the results of treatment of chronic endometritis were studied.
Results and Discussion. The groups did not differ by the obstetric-gynecological, somatic anamnesis, complaints, underlying and concomitant pathology. It should be noted that the most frequent pathology of the endometrium, detected in women with chronic endometritis, were endometrial polyps (28.6 % and 33.6 %). A study of the long-term results of CE treatment showed that the newly diagnosed pathology of the uterine cavity in the group I was recorded significantly less often (by 1.9 times, p <0.05), while the pregnancy rate was 3.1 times higher (p < 0.05). As a result of the treatment, virtually all patients have disappeared complaints of cycle disorders and abdominal pain. Among women in group I, there were no adverse reactions to intrauterine administration of the ozonized solution.
Conclusions. The study made it possible to conclude that the use of ozonotherapy in the complex treatment of chronic endometritis in late reproductive and premenopausal ages can significantly increase the effectiveness of treatment, reduce the frequency of newly detected intrauterine pathology, in particular, the uterine myoma, and increase the frequency of pregnancy.
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