CORRECTION OF LACTOSE DEFICIENCY IN INFANTS WITH SYMPTOMS OF ALLERGY TO FOODS

Authors

  • O. A. Stroy ДВНЗ ТДМУ ім. І.Я. Горбачевського, видавництво "Укрмедкнига"
  • L. V. Slipachuk Національний медичний університет імені О.О. Богомольця, місто Київ
  • A. N. Antoshkina Національний медичний університет імені О.О. Богомольця, місто Київ
  • L. N. Kazakova Національний медичний університет імені О.О. Богомольця, місто Київ

DOI:

https://doi.org/10.11603/24116-4944.2017.2.7796

Keywords:

food allergies, gastrointestinal syndrome, lactase deficiency, drug lactase.

Abstract

The aim of the study – to investigate an effort of correcting lactose deficiency to the health of infants with symptoms of allergy to foods.

Materials and Methods. The study involved 35 children aged 2 to 14 months with food allergy. The study included patients with lactase deficiency predictable for the previous definition of fecal pH values (below 5.5). Children underwent general clinical examination, scatological study the definition of fecal pH, crop fecal bacteria overgrowth dynamics.

Results and Discussion. In all the children we recorded certain manifestations of food allergy. The children were on breast feeding – 16 (45.7 %), partially breastfed – 14 (40 %) and artificial – 5 (14.3 %) feeding. In the study of microbial landscape of the intestine in most children the total number of E.coli remained in the normal range. Reducing the number of bifid bacteria and lactobacilli observed respectively in 25.7 % and 60.0 % of patients. The most observed children had pathogenic micro flora. All children after examination were prescribed the treatment that included hypoallergenic diet for breastfeeding mother and / or child, enzyme replacement therapy with lactase "Mamalak." Product – drops containing 1 ml solution in 3000 ALU lactase. The drug was administered at the rate of 750 ALU of lactase (5 drops) per 100 ml of breast milk or replacement before each
feeding period of 60 days. Every 3-rd child had clinical improvement of skin- and gastrointestinal syndromes (11–31.4%). A part of children (approx. 25 %) had positive changes in the intestinal micro flora. An amount of children rose till the end of observation up to 29 (82.9 %).

Conclusions. Infants having symptoms of allergy to food can get formed lactose deficiency. Addition of lactase medicine to
complex therapy is recommended for allergic diseases contributed to the health improvements of children in most cases.

Author Biographies

O. A. Stroy, ДВНЗ ТДМУ ім. І.Я. Горбачевського, видавництво "Укрмедкнига"

кандидат медичних наук, асистент кафедри педіатрії № 1 НМУ

L. V. Slipachuk, Національний медичний університет імені О.О. Богомольця, місто Київ

кандидат медичних наук, асистент кафедри педіатрії № 1 НМУ

A. N. Antoshkina, Національний медичний університет імені О.О. Богомольця, місто Київ

кандидат медичних наук, доцент кафедри педіатрії № 1 НМУ

L. N. Kazakova, Національний медичний університет імені О.О. Богомольця, місто Київ

кандидат медичних наук, асистент кафедри педіатрії № 1 НМУ

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Published

2017-10-04

How to Cite

Stroy, O. A., Slipachuk, L. V., Antoshkina, A. N., & Kazakova, L. N. (2017). CORRECTION OF LACTOSE DEFICIENCY IN INFANTS WITH SYMPTOMS OF ALLERGY TO FOODS. Actual Problems of Pediatrics, Obstetrics and Gynecology, (2). https://doi.org/10.11603/24116-4944.2017.2.7796

Issue

Section

PEDIATRICS