SOME ASPECTS OF THE IMPACT OF THYROID DYSFUNCTION ON THE OCCURRENCE OF UTERINE LEIOMYOMA
DOI:
https://doi.org/10.11603/24116-4944.2017.2.7793Keywords:
uterine leiomyoma, thyroid gland, hormonal imbalance, еmbolization of uterine arteries.Abstract
This article presents the development of the modern views of the most common gynecological pathology of uterine leiomyoma. We made the analysis of the occurrence of the disease due to the changes in hormonal, immune balance of the body and the role of genetic factors in the process. Also, the disturbances of the thyroid function in the development of the hyperplastic processes of the reproductive system were studied. The article points to the necessity of choosing therapies which can save the female reproductive function and improve the quality of life in the postoperative period. The uterine leiomyoma is not the disease of one organ but of the whole organism. The article shows that the treatment and the prevention of recurrence of myoma need the set of activities, which are aimed at the regulation of relations of the hypothalamic-pituitary-ovarian system and are designed to impaire the regulation of metabolic and immune homeostasis recovery of peripheral hemodynamics, eliminating inflammation. We studied the results of the using of different groups of drugs. The using of the antiprogesterone drugs and substances that modulate the activity of progesterone receptors and may be used in the treatment of uterine leiomyoma is presented.References
Tatarchuk, T. F. & Kosey, N. V. (2008). Dyferentsyalnyye podkhody k organosokhariayushchey terapii leyomiomy matky v razlychnyye vozrastnyye periody [Differential approaches to organ-preserving therapy of uterine leiomyoma in different age periods]. Medytsynskyye aspekty zdorovya zhenshchyny – Medical aspects of women's health, 4, 24–29 [in Russian].
Ming-Huei Cheng. Uterine myoma: a condition amendable to medical therapy? Ming-Huei Cheng, Peng-Hui Wang. (2008). Expert Opinion on Emerging Drugs., 13, (Is. 1), 119-133.
Buyanova, S. N., Mheliashvily, M. V., & Petrakova, S. A. (2008). Sovremennyye predstavleniya ob etyologii, patoheneze i morfoheneze miomy matky [Modern ideas about the etiology, pathogenesis and morphogenesis of uterine myomas]. Rossiyskyi vestnik akushera-ginekologa – The Russian bulletin of the obstetrician-gynecologist, 6, 45–51 [in Russian].
Stryzhakov, A. N. (2008). Mioma matky: patohenez, diahnostika, lyecheniye [Myoma of the uterus: pathogenesis, diagnosis, treatment]. Voprosy ginekologii, akusherstva I perynatologii – Questions of gynecology, obstetrics and perinatology, 4, 7–18 [in Russian].
Tropeano, G. Amoroso, S., Stasi C. (2011). The timing of natural menopause after uterine fibroid embolization: a prospective cohort study. Fertil Steril, 96, 980–984.
Malyshkina, A. I., Fetysova, I. N., Diuzhev, Zh. A., Sytnikova, O. H., & Dobrynina, M. L. (2011). Deletsyy genov hlytation-S-transferaz I oksydativnyy stress kak faktora bystroho rosta miomy matky [Deletion of glutathione-S-transferase and oxidative stress as factors of rapid growth of uterine fibroids]. Aktualni pytannia pediatrii, akusherstva ta hinekolohii – Current issues of obstetrics and gynecology, 1, 213–216 [in Ukrainian].
Sydorova, I. S., Unanian, A. L., Kohan, Ye. A., & Huriyev, T. D. (2012). Mioma matky u bolnykh molodoho vozrasta: kliniko-patoheneticheskiye osobennosty [Myoma of the uterus in patients of young age: clinical and pathogenetic features]. Akusherstvo, hinekolohiya, reproduktsiya – Obstetrics, Gynecology, Reproduction, 1, (4), 16–20 [in Russian].
Ivaniuta, L. I. & Ivaniuta, I. S. (2012). Histeroskopichna otsinka stanu matky u zhinok z leyomiomoiu matky ta dysfunktsionalnymy zakhvoriuvanniamy molochnoi zalozy [Hysteroscopic evaluation of the uterus in women with dysfunctional uterine leiomyoma and breast disease]. Aktualni pytannia pediatrii, akusherstva ta hinekolohii – Current issues of obstetrics and gynecology, 2, 55–57 [in Ukrainian].
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