PINEAL GLAND, REPRODUCTIVE SYSTEM AND PREGNANCY
DOI:
https://doi.org/10.11603/24116-4944.2017.1.7584Keywords:
pregnancy, pineal gland, melatonin.Abstract
The aim of the study – to establish the link between the functioning of pineal gland, reproductive system and pregnancy.
Materials and Methods. The research was conducted on 20 adult non-linear female nulliparous white rats Rattus Norvegicus Wistar (study group). Control group included 16 female rats with the same parameters. After occurrence of pregnancy the rats were exposed to light 24 hours/day by halogen lights of “white” light, meanwhile the rats of control group had a regimen “12 hours of light/12 hours of darkness”. After 21 days of confirmed pregnancy the rats were slayed. The uteruses of the rats underwent pathohistological examination.
Results and Discussion. The discontinuation of the pregnancy development was found in all rats of study group, whereas in control group pregnancies developed normally. Pathohistological examination confirmed the changes of endometrium typical for pregnancy.
Conclusion. The depression of function of pineal gland, caused by enlightenment, has a direct impact on pregnancy process and can be a reason of pregnancy termination.
References
Hryshchenko, V.I. (1979). Rol epifiza v fiziologii i patologii zhenskoi polovoi sistemy [Role of pineal gland in physiology and pathology of female reproductive system]. Kharkiv: Vyshcha Shkola [in Russian].
Pishak, V.P. (2002). Shyshkopodibne tilo – mistse i rol u khronorytmo-lohichniy orhanizatsii fiziolohichnykh funktsiy [Pineal gland – place and role in chronorhythmologic organization of physiologic functions]. Bukovynskyi medychnyi visnyk – Bukovinian Medical Journal, 3-4, 4-6 [in Ukrainian].
Pishak, V.P. & Bulyk, R.Ye. (2006). Mekhanizmy uchasti shyshkopodibnoi zalozy v zabezpechenni tsirkadiannoi rytmichnosti fiziologichnykh funktsiy [Mechanisms of participation of pineal gland in maintenance of rhythmicity of physiologic functions]. Bukovynskyi medychnyi visnyk – Bukovinian Medical journal, 4, 4-7 [in Ukrainian].
Podolskyi, V.V. & Khomynska, Z.B. & Teterin, V.V. & Hulchiy, M.M. (2005). Rol hormoniv epifiza v systemi antystresornoho zahystu orhanizmu pry psykhoemotsiynomu stresi u zhinok fertylnoho viku [Role of the hormones of pineal gland in system of anti-stress protection of organism in case of psycho-emotional stress in women of reproductive age]. Visnyk naukovykh doslidzhen – Journal of Scientific Researches, 2, 84-86 [in Ukrainian].
Podolskiy, V.V. & Khomynska, Z.B. & Dronova, V.L. (2005). Rol epifiza v neiroendokrinnoi regulatsii protsessov reproduktsii i adaptatsii [Role of pineal gland in neuro-endocrine regulation of the processes of reproduction and adaptation]. Zdorovye zhenshchiny – Woman’s Health, 1, 91-95 [ in Russian].
Reiter, R.J. & Tan, D.X., & Burkhardt, S. (2002). Reactive oxygen and nitrogen species and cellular and organismal decline: amelioration with melatonin. Mechanisms of Ageing and Development, 123, 1007-1009.
Richter, H.G. & Hansell, J.A. & Raut, Sh. & Giussani, D.A. (2009). Melatonin improves placental efficiency and birth weight and increases the placental expression of antioxidant enzymes in undernourished pregnancy. Journal of Pineal Research, 46, 357 – 364.
Chawdhury, I. & Sengupta, A. & Maitra, S.K. (2008). Melatonin: Fifty years of scientific journey from the discovery in bovine pineal gland to delineation of functions in human. Indian Journal of Biochemistry and Biophysics, 45, 289-304.
Hardeland, R. & Tan, D.X. & Reiter, R.J. (2009). Kynuramines, metabolites of melatonin and other indoles: The resurrection of an almost forgotten class of biogenic amines. Journal of Pineal Research, 47, 109-126.
Zapadniuk, I.P. & Zapadniuk, V.I. & Zakharia, Ye.A. & Zapdniuk, B.V. (1984). Laboratornuye zhyvotnye: razvedenie, soderzhaniye, ispolzovanie v eksperimente [Laboratory animals: breeding, keeping, usage in experiment]. Kyiv: Vyshcha shkola [in Russian].
Milovanov, A.P. (1999). Patologiya sistemy “Mat-placenta-plod” [Pathology of the system “Mother-placenta-fetus”]. Moscow: Meditsina [in Russian].
Downloads
Published
How to Cite
Issue
Section
License
Authors who publish in this journal agree to the following terms:
1. The authors reserve the right to authorship of the work and pass the journal right of first publication of this work is licensed under a Creative Commons Attribution License, which allows others to freely distribute the work published with reference to the authors of the original work and the first publication of this magazine.
2. Authors are entitled to enter into a separate agreement on additional non-exclusive distribution of work in the form in which it was published in the magazine (eg work place in the electronic repository institution or publish monographs in part), provided that the reference to the first publication of this magazine.
3. Policy magazine allows and encourages authors placement on the Internet (eg, in storage facilities or on personal websites) manuscript of how to submit the manuscript to the editor and during his editorial processing, since it contributes to productive scientific discussion and positive impact on the efficiency and dynamics of citing published work (see. The Effect of Open Access).