PROGNOSTIC CRITERIA OF THE THREAT ANTENATAL FETUS DEATH IN THE CONGENITAL DEVELOPMENT PERILS
DOI:
https://doi.org/10.11603/24116-4944.2017.1.7560Keywords:
congenital malformations, antenatal fetal death, Doppler velocimetry.Abstract
The aim of the study – to monitor the dynamic tenatogenesis of intrauterine fetuses with birth defects. The dynamics of fetal tenatogenesis was observed in 24 fetus that had congenital defects.
Materials and Methods. These patients undergo daily Doppler velocimetry in the uterine arteries, umbilical artery and mesencephalic arteries and low-frequency piezoelectric thromboelastography from the date of registration and threatening signs until the statement of intrauterine fetal death. We determined the correlation coefficients between the method of Spearman and quantitative indicators likely antenatal fetal death.
Results and Discussion. Analysis of the data showed that only flow disturbances in uterine the artery risk of antenatal fetal death is absent. In violation of blood flow in the umbilical artery and the combination of these disorders of hypercoagulation high probability of antenatal fetal death over from 2–3 to 7–14 whith days. The highest risk antenatal fetal death within 2-4 hours due to violation of blood flow in the medium cerebral artery against the background of a hypercoagulable state and inhibition of fibrinolysis.
Based on the performance evaluation of blood flow in vessels feto-placental complex and hemostasis by low-frequency piezoelectric thromboelastography in pregnant women with congenital malformations of the fetus, combined with placental dysfunction, we developed a method of forecasting risk antenatal fetal death, which is the assessment of hemodynamics fetus (Doppler) with simultaneous study of low frequency piezoelectric thromboelastography. In finding violations of blood flow in the umbilical artery, or (and) medium cerebral artery combined with hypercoagulation and inhibition of fibrinolysis, recommended urgent accouchement throughout the day.
Conclusions. The proposed algorithm of pregnancy, delivery and examination leads to a lack of antenatal fetal death, perinatal decrease of mortality, perinatal morbidity.
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