THE PECULIARITIES OF THE FETOPLACENTAL COMPLEX DEVELOPMENT IN PREGNANT WOMEN WITH VARICOSE LEGS
DOI:
https://doi.org/10.11603/24116-4944.2017.1.7377Keywords:
varicose disease, placental dysfunction, pregnancy complications.Abstract
The aim of the study – to decrease the frequency of perinatal pathology in women with varicose legs based on the study of peculiarities of the fetoplacental complex, its development and functioning as well as the main clinical and hemostasiological parameters. Another tool to decrease the frequency of perinatal pathologies is considered to be the improvement of diagnostics and treatment, namely, the implement of differentiated approach.
Materials and Methods. Pregnant women were divided into groups. The first group included 60 pregnant women with varicose legs receiving traditional treatment; the second group – 60 pregnant women with varicose legs receiving our treatment; and the control group – 30 obstetrically and somatically healthy pregnant women (natural delivery).
The research was conducted using such methods as clinical, functional (echographics, cardiotocographics, dopplerometry), endocrinological, hemostasiological, assessment of endothelial dysfunction, morphological and statistical.
Results and Discussion. The studies reveal that the 1st part of pregnancy in Groups 1 and 2 were characterized by a row of complications, as follows: chronic venous insufficiency (group 1 – 80 %; group 2 – 80 %); placental insufficiency (group 1 – 63.3 %; group 2 – 60 %). Threatened miscarriage constituted correspondingly 40.0 and36.6 in group 1 and 2. Bacterial vaginosis occurred much less often (group 1 – 26.6 %; group 2 – 33.3 %) and early toxicosis, too (group 1 – 23.3 %, group 2 – 20.0 %).
Regarding the high level of various complications occurring in the first half of pregnancy, we studied the main clinical, laboratory and functional parameters in 22 week of gestation in order to estimate the functional state of the fetoplacental complex.
Conclusions. According to the result of the research, the high risk of perinatal pathology developing is due to the changes in the functional biosystem “mother – placenta – fetus” caused by the varicose disease of lower extremities, namely, in hemodynamic parameters. This must be taken into consideration when it comes to treatment and predicting measures.
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