PECULIARITIES OF GENITAL ENDOMETRIOSIS ASSOCIATED WITH INFERTILITY
DOI:
https://doi.org/10.11603/24116-4944.2022.2.13451Keywords:
endometriosis, adenomyosis, infertilityAbstract
The aim of the study – to conduct a comparative retrospective analysis of the medical histories of patients with endometriosis associated with infertility and patients with tubo-peritoneal factor infertility
Materials and Methods. A retrospective analysis of 485 patient’s medical histories, who applied to the medical centre “Yuzko Medical Center” regarding infertility for the period 2019–2022 was conducted. The main group (I) consists of 435 women with infertility, associated with endometriosis. The control group (II) consists of 50 women with tubal-peritoneal infertility factor. The obtained results were processed by the method of variational statistics.
Results and Discussion. It has been founded that women with infertility associated with endometriosis, pain syndrome is noted for 305 patients (70.2 %). The dependence of the pain syndrome on menstruation was noted for 60.2 % of cases. Primary infertility was detected in 40.3 % of patients of group I and 84.6 % of group II, secondary infertility was diagnosed in 38 % of patients group I and 21 % of patients of group II. According to the results of the cytological examination, it was found that type II – 320 women (73.6 %) predominates and 10 women (21.3 %) of the control group. Type I – 114(26.4 %) women of the main group and 42 women (84.6 %) of the control group.
Conclusions Thus, modern medicine should continue to study in detail the diseases that cause infertility. Scientists should investigate the causes of infertility formation in order to their further prevention and successful treatment. According to repeated ultrasound data, internal genital endometriosis is not suspected, therefore, it is not possible to rely on ultrasound data as an additional research method, and this requires the discovery of new diagnostic methods.
References
Yaseen, E.M. (2018). Follow up of women after laparoscopy versus laparotomy in emergency gynecological problems. Med. J. Tikrit University, 24(1), 109-127. DOI: 10.25130/mjotu.24.01.11.
Sharma, R., Biedenharn, K.R, Fedor, J.M., & Agarwal, A. (2013). Lifestyle factors and reproductive health: taking control of your fertility. Reprod. Biol. Endocrinol., 11, 66. DOI: 10.1186/1477-7827-11-66.
Kimberly, L., & Case, A. (2011). Advanced reproductive age and fertility. Int. J. Gynecol. Obstet., 33(11), 1165-1175. DOI: 10.1016/S1701-2163(16)35087-3.
Lin, K., Samantha, B., Sammel, M.D., & Barnhart, K.T. (2010). Risk factors for diminished ovarian reserve and the role of endometriosis. Fertil. Steril., 94(4), S63. DOI: 10.1016/j.fertnstert.2010.07.247.
Bellver, J., Melo, M.A., Bosch, E., Serra, V., Remohi, J., & Pellicer, A. (2007). Obesity and poor reproductive outcome: The potential role of the endometrium. Fertil. Steril., 88(2), 446-451. DOI: 10.1016/j.fertnstert.2006.11.162.
Clark, A.M., Thornley, B., Tomlinson, L., Galletley,C., & Norman, R.J. (1998). Weight loss in obese infertile women results in improvement in reproductive outcome for all forms of fertility treatment. Hum. Reprod., 13(6), 1502-1505. DOI: 10.1093/humrep/13.6.1502.
Freizinger, M., Franko, D.L., Dacey, M., Okun, B., & Domar, A.D. (2010). The prevalence of eating disorders in infertile women. Fertil. Steril., 93(1), 72-78. DOI: 1016/j.fertnstert.2008.09.055.
Shafik, A., Ratcliffe, N., & Wright J.T. (2009). Importance of histological diagnosis in patients with pelvic pain and laparoscopic evidence of endometriosis. Gynecol. Endosc., 9, 301-304. DOI: 1046/j.1365- 2508.2000.00366.x.
Bouquet, De Jolinière, J., Ayoubi, J.M., Gianaroli, L., Dubuisson, J.B., Gogusev, J., & Feki, A. (2014). Endometriosis: a new cellular and molecular genetic approach for understanding the pathogenesis and evolutivity. Front. Surg., 27(01), 16. DOI: 10.3389/fsurg.2014.00016.
Acién, P., & Velasco I. (2013). Endometriosis: a disease that remains enigmatic. ISRN Obstet. Gynecol., 2013, 242149. DOI: 10.1155/2013/242149.
Khan, K.N., Kitajima, M., Inoue, T., Fujishita, A., Nakashima, M., & Masuzaki, H. (2015). 17β-estradiol and lipopolysaccharide additively promote pelvic inflammation and growth of endometriosis. Reprod. Sci., 5, 585-594. DOI: 10.1177/1933719114556487.
Cakmak, H., Guzeloglu-Kayisli, O., Kayisli, U.A., & Arici, A. (2009). Immune-endocrine 17interactions in endometriosis. Front. Biosci. (Elite Ed)., 1, 429-443.
Khan, K.N., Kitajima, M., & Hiraki, K. (2010). Changes in tissue inflammation, angiogenesis and apoptosis in endometriosis, adenomyosis and uterine myoma after GnRH agonist therapy. Hum. Reprod., 25(3), 642-653. DOI: 10.1093/humrep/dep437.
Young, V.J., Browns, J.K., Saunders, P.T., & Horne, A.W. (2013). The role of the peritoneum in the pathogenesis of endometriosis. Hum. Reprod. Update., 19(5), 558-569. DOI: 16.1093/humupd/dmt024.
Macer, M.L., & Taylor, H.S. (2012). Endometriosis and infertility: a review of the pathogenesis and treatment of endometriosis–associated infertility. Obstet. Gynecol. Clin. North Am., 39(4), 535-549. DOI: 10.1016/j.ogc.2012.10.002.
Giudice, L.C. (2010). Clinical practice. Endometriosis. N. Engl. J. Med., 362(25), 2389-2398. DOI: 10.1056/ NEJMcp1000274.
Robboy, S.J., & Bean, S.M. (2010). Pathogenesis of endometriosis. Reprod. Biomed. Online., 21(1), 4-5. DOI: 10.1016/j.rbmo.2010.03.031.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Actual Problems of Pediatrics, Obstetrics and Gynecology
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish in this journal agree to the following terms:
1. The authors reserve the right to authorship of the work and pass the journal right of first publication of this work is licensed under a Creative Commons Attribution License, which allows others to freely distribute the work published with reference to the authors of the original work and the first publication of this magazine.
2. Authors are entitled to enter into a separate agreement on additional non-exclusive distribution of work in the form in which it was published in the magazine (eg work place in the electronic repository institution or publish monographs in part), provided that the reference to the first publication of this magazine.
3. Policy magazine allows and encourages authors placement on the Internet (eg, in storage facilities or on personal websites) manuscript of how to submit the manuscript to the editor and during his editorial processing, since it contributes to productive scientific discussion and positive impact on the efficiency and dynamics of citing published work (see. The Effect of Open Access).