PREVENTION OF DISORDERS OF FUNCTIONAL DIFFERENTIATION OF THE PLACENTA
DOI:
https://doi.org/10.11603/24116-4944.2020.2.11847Keywords:
functional differentiation of the fetal part of the placenta, distress, echogenicity, preventionAbstract
The aim of the study – the possibility of prevention of complications of the gestational process.
Materials and Methods. The first group of observations consisted of 25 women who at 28–30 weeks of gestation had initial signs of fetal dysfunction.The second group consisted of 25 women who were prescribed vaginally micronized progesterone proginorm gesta 200 mg per day to prevent premature birth from 22–24 weeks of gestation. The third group consisted of 25 pregnant women at risk of functional differentiation of the placenta, who from 22 weeks of pregnancy took progesterone 200 mg per day vaginally. Evaluation of fetal development was performed using an ultrasound system SA-8000 EX. Cardiotachogram was recorded with a Hewlett-Packard 8030 A monitor.
Results and Discussion. The average biophysical profile of the fetus (BPF) in pregnant women of the first group was (5.6±0.3) points. The basal heart rate (BHR) was (171.3±4.3) bpm, there was undulating type of variability. Amplitude of instantaneous oscillations – (3.4±0.5) bpm, frequency – (3.0±0.4) bpm, single (2.2±0.3) accelerations of moderate amplitude were registered (16.5±0.8) bpm) and duration (17.8±1.6) s). In 24 % of cases, individual (1.5±0.4) decelerations were noted. In the first group, in 48 % of cases the placenta was highly echogenic. In women of the second group found fetal distress in 12 % of cases. In the third group, disorders of functional differentiation of the fetal part of the placenta occurred in 24 % of pregnant women.
Conclusions. Appointment of proginorm gesta to pregnant women has a positive effect of functional differentiation of the fetal part of the placenta, provides prevention of fetal distress.
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