QUALITY OF LIFE OF WOMEN WITH ENDOMETRYOSIS AND DIFFICULTIES OF THE THYROID DISEASE FUNCTION
DOI:
https://doi.org/10.11603/1811-2471.2017.v1.i3.8205Keywords:
genital endometriosis, dysfunction of thyroid gland, quality of life, psychoemotional condition.Abstract
According to the purpose and aims of the study, 130 patients of reproductive age with EM were included in the study, who underwent organo-preservation surgery – a convex cystectomy. Among them 90 patients were with a violation of the function of the thyroid gland.
In the course of the investigation, it has been updated, as much as the affected effect employs EM in any life of women. Thus, in the general group of 3 (36.66 %) patients in the main group and 11 (27.5 %) in the treatment comparison group, each life was considered as low, while only 5.0 % of the control subjects had a similar characteristics of life.
The use of an optimized treatment complex using GHG and mastodinone agonists in postoperative correction of hormonal imbalances has a positive effect on psychoemotional and vegetative-vascular manifestations, contributed to the approximation of the level of all parameters of the quality of life to the control indicators, which allowed not only to improve the basic indicators of hormonal homeostasis, but also to achieve restoration of reproductive function.
Our proposed treatment scheme for EM is not activated, and it opens new prospects in the prevention of the development of hyperplastic processes of endometrium, their growth and the growth of the percentage of probable relapses and non-surgical operative interventions, and as a consequence, preserving the reproductive potential of a woman.
References
Adamyan, L.V., Andreyeva, Ye.N., Apolikhina, I.A., Bezhenar, V.F., Gevorkyan, M.A., Gus, A.I. & Demidov, V.N. (2013). Endometrioz: diagnostika, lecheniye i reabilitatsiya [Endometriosis: diagnosis, treatment and rehabilitation]. Federalnyye klinicheskiye rekomendatsii po vedeniyu bol- nykh – Federal Clinical Guidelines for Managing Patients. Moscow [in Russian].
Boiko, V.I., Nikitina, I.M. & Yezhova, O.V. (2016). Su- chasni aspekty likuvannia endometriozu yaiechnykiv [Mo- dern aspects of the treatment of ovarian endometriosis]. Akusherstvo. Hinekolohiia. Henetyka. – Obstetrics. Gyneco logy. Genetics, 3 (2), 47-51 [in Ukrainian].
Boychuk, A.V., Kurylo, O.Yu., Korman, O.M. & Khli- bovska, O.I. (2015). Orhanozberihaiuche khirurhichne liku- vannia ta chastota retsydyviv endometriozu [Organ-pre- serving surgical treatment and the frequency of endometriosis relapse]. Aktualni pytannia pediatrii, akush- erstva ta hinekolohii – Actual Issues of Pediatrics, Obstetrics and Gynecology, 2, 73-77 [in Ukrainian].
Boichuk, A.V. & Kurylo, O.Yu. (2016). Ovarialnyi rezerv zhinok z endometrioidnymy kistamy [Ovarian reserve of women with endometrioid cysts]. Zbirnyk naukovykh prats Asotsiatsii akusherivhinekolohiv Ukrainy – Collection of Sci- entifi Works of the Association of ObstetriciansGynecolo- gists of Ukraine, 2 (38), 60-66 [in Ukrainian].
Galkina, N.V., Mazurina, N.V. & Troshina, Ye.A. (2006). Diffuznyy eutireoidnyy zob (epidemiologiya, eti- ologiya i patogenez, rol geneticheskikh faktorov v razvitiyi, lecheniye) [Diffuse euthyroid goiter (epidemiology, etio- logy and pathogenesis, the role of genetic factors in deve- lopment, treatment)]. Probl. endokrinologii – Problems of Endocrinology, (52), 4, 49-56 [in Russian].
Deryabina, Ye.G. & Bashmakova, N.V. (2008). Sovre- mennyye predstavleniya o vliyanii polovykh steroidov na patogenez zabolevaniy shchitovidnoy zhelezy u zhensh- chin [Modern ideas about the effect of sex steroids on the pathogenesis of thyroid diseases in women]. Ross. vest. akush. ginek. – Russian Journal of ObstetriciansGynecolo- gists (8), 6, 52-55 [in Russian].
Zaporozhan, V.M., Tatarchuk, T.F. & Kaminskyi, V.V. (2015). Natsionalnyi konsensus shchodo vedennia patsi- ientok iz endometriozom [National Consensus on the Ma- nagement of Patients with Endometriosis]. Reproduktiv naya endokrinologiya – Reproductive Endocrinology, 4, 7-12 [in Ukrainian].
Ishchenko, A.I., Kudrina, Ye.A. & Abdullayeva, U.A. (2006). Effektivnost kombinirovonnogo lecheniya naruzh- nogo endometrioza s sindromom khronicheskikh tazovykh boley s ispolzovaniyem agonista gonadotropin-rilizing gor- mona Dekapeptil-depo [Efficiency of combined treatment of external endometriosis with the syndrome of chronic pelvic pain with the use of agonist gonadotropin-releasing hormone Decapeptil Depot]. Zhinochyi likar – Women’s doctor, 6 (8), 8-11 [in Russian].
Ishchenko, A.I., Kudrina, Ye.A. & Stanoyevich, I.V. (2017). Sovremennyye problemy naruzhnogo genitalnogo endometrioza [Modern problems of external genital en- dometriosis]. Akush. i ginek. – Obstetrics and Gynecology, 5, 67-73 [in Russian].
Leonov, B.V., Kulakov, V.I. & Smolnikova, V.Yu. (2003). Primeneniye a-GnRG pri besplodii [Application of a-GnRH in infertility]. Akushcherstvo i ginekologiya – Ob- stetrics and Gynecology, 4, 1-4 [in Russian].
Nakaz Ministerstva okhorony zdorovia Ukrainy 06.04.2016 № 319 Unifikovanyi klinichnyi protokol pervyn- noi, vtorynnoi (spetsializovanoi) ta tretynnoi (vysokospe- tsializovanoi) medychnoi dopomohy. Taktyka vedennia patsiientok z henitalnym endometriozom [Order of the Ministry of Health of Ukraine 06.04.2016 No. 319 Unified clinical protocol of primary, secondary (specialized) and tertiary (highly specialized) medical care. Tactics of pa- tients with genital endometriosis]. [in Ukrainian].
Pashkov, V.M. & Lebedev, V.A. (2007). Sovremen- nyye predstavleniya ob etiologii i patogeneze genitalnogo endometrioza [Modern ideas about the etiology and pathogenesis of genital endometriosis]. Vopr. ginek., akush. i perint. – Issues of Gynecology, Obstetrics and Perina- tology, (6), 3, 52-61 [in Russian].
Fernandez, I., Reid, C. & Dziurawiec, S. (206). Living with endometriosis: The perspective of male partners. J. Psychosom. Res., 61 (4), 433-438.
Hickey, M., Ballard, K. & Farquhar, C. (2014). Endo- metriosis. BMJ, 348, g1752.
Stratton, P. & Berkley, K.J. (2011). Chronic pelvic pain and endometriosis: translational evidence of the rela- tionship and implications. Hum. Reprod. Update, (17), 3, 327-324.
Trokoudes, K.M., Skordis, N. & Picoloc, M.K. (2006). Infertility and thyroid disorders. Curr. Opin. Obstet. Gyne- col, (18), 4, 446-451.
Wu, Y., Kajdacsy-Balla, A. & Strawn, E. (2006). Tran- scriptional characterizations of differences between eu- topic and ectopic endometrium. Endocrinology, (47), 1, 232-246.
