MELDONIUM APPLICATION IN REHABILITATION OF PATIENTS WITH CHRONIC PANCREATITIS COMBINED WITH STABLE CORONARY ARTERY DISEASE
DOI:
https://doi.org/10.11603/1811-2471.2017.v0.i1.7440Keywords:
chronic pancreatitis, stable coronary heart disease, metabolic therapy, meldonium, sequential introduction.Abstract
One of the few ways to restore normal operation of all the vital organs and systems is the use of metabolic therapy.
The aim of the work was to investigate the effectiveness of a course of treatment for metabolic drug meldonium to correct prooxidant-antioxidant and trophologic disorders in patients with comorbid course of chronic pancreatitis (CP) and stable coronary artery disease (SCAD). The study included 90 patients with CP combined with SCAD who were divided into two groups (depending on treatment programs): I group (45 patients) received the standard treatment (ST); II group (45 patients) except ST received drug meldonium (Vazonat) with sequential introduction as follows: first grade – 5 ml intravenous bolus injection 1 per day for 10 days; the second stage – the introduction of meldonium electrophoresis on a part of the left upper quadrant a day for 15 days; third degree – taking the drug further 2 capsules 1 time per day for a month.
Results. It was proved that the addition to the treatment of patients with comorbidity CP and SCAD meldonium with sequential introduction is more conducive to improving the performance and trophological pro-oxidant-antioxidant states than the standard basic therapy.
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