PECULIARITIES OF CHANGES IN THE LIPID PROFILE AND HEMOSTASIS SYSTEM IN WOMEN WITH MODERATE PREECLAMPSIA AGAINST METABOLIC SYNDROME
DOI:
https://doi.org/10.11603/1811-2471.2022.v.i1.13003Keywords:
preeclampsia, metabolic syndrome, cholesterol, triglycerides, lipoproteinsAbstract
SUMMARY. The course of pregnancy in women with metabolic syndrome is characterized by a high risk of complications. Therefore, early diagnosis and assessment of severity are key to preventing maternal and perinatal mortality.
The aim – to optimize and study the correlations between lipid profile and hemostasis system in patients with moderate preeclampsia on the background of metabolic syndrome.
Material and Methods. The work is based on the results of a comprehensive survey of 46 pregnant women with moderate preeclampsia, whose pregnancies took place against the background of metabolic syndrome. Patients were divided into groups depending on the proposed modified treatment.
Results. Analyzing the results, it was found that patients in the study groups were characterized by a 1.2-fold increase in cholesterol in women of both groups, a 2.7-fold increase in triglycerides, a decrease in high-density lipoprotein and a moderate increase in low-density lipoprotein. Evaluating the data, the presence of additional diagnostic markers of metabolic syndrome in patients of groups I and II of the examined groups was established.
Conclusion. It is established that the level of fibrinogen significantly increases depending on the severity of the course. Changes in the blood lipid profile are characterized by an increase in triglycerides, low-density lipoprotein, and a decrease in the level of high-density lipoprotein, which leads to the formation of hypertension, visceral obesity, hyperinsulinemia and dyslipidemia.
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