EFFECT OF XEROGEL ON THE MICROFLORA OF THE LARGE INTESTINE
DOI:
https://doi.org/10.11603/1811-2471.2021.v.i4.12807Keywords:
enterosorbents, xerogel, microflora, enterosorption, large intestineAbstract
SUMMARY. A lot of attention we paying for methods of treatment wich can cleanse internal environment of our body and remove foreing substances from the body of a sick person.
The aim – to characterise of the effect of enterosorbent on the microflora of the colon.
Material and Methods. The study was conducted on 50 white laboratory rats with an average weight of 200 grams, who were divided into control and experimental groups. The first group consisted of intact rats, the feeding of which was standard. Other rats, which were given Xerogel during normal feeding. In both groups of white rats, the content of the colon was studied, which was obtained using a bacteriological method. The European Convention on the Protection of vertebrate animals used for experimental and other scientific purposes (Strasbourg, 1986).
Results. After 7 and 14 days of taking xerogel, the intestinal stick content in the feces increased by 14 % and 13 %. The content of lactose-negative enterobacteria under the influence of xerogel on the 7th day did not change. On the 14th day the number of lactose-negative enterobacteria decreased under the influence of xerogel by 9 %. After the 7th day of taking xerogel, the content of epidermal staphylococcus decreased by 12 %. During 14 days significantly reduced the content of epidermal staphylococcus by 11.1 %, as well as gold staphylococcus by 20 %. Taking Xerogel on the 7th day of the experiment increased the number of enterococci by 7 %. Enterococcal content in the large intestines of the trial rats increased by 8.36 % after 14 days of taking xerogel. In the feces of the trial rats after 14 days of taking xerogel, the number of bifido and lactobacteria also increased by 36.5 % and 39.3 %, respectively. In relation to anaerobic microorganisms, Xerogel was not significantly affected. Xerogel had a positive effect on microbiocenosis after the 7th day of feeding – the amount of protein decreased by 20 %, and after the 14th day – by 32 %. After taking xerogel, the number of these microorganisms decreased by 17 % (7th day) and 39 % (14th day).
Conclusions. An increase in the content of bifido-, lactobacteria, non-pathogenic bowel sticks and enterococci, as well as a decrease in the number of protea, gold staphylococcus and fungi of the genus Candida in the thick intestine of rats caused the reception of xerogel, which led to the normalization of microbiocenosis, a violation of which was noted in animals of the control group on a fiber-free diet.
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