THROMBOCYTOGRAM PARAMETERS IN PATIENTS OF EARLY RECOVERY PERIOD OF ISCHEMIC STROKE
DOI:
https://doi.org/10.11603/1811-2471.2021.v.i2.12211Keywords:
thrombocytogram, platelet size, thrombocrit, early recovery period of ischemic strokeAbstract
According to the results of the thrombocytogram in patients with ischemic stroke in the early recovery period there are morphofunctional changes in platelets.
The aim – changes in thrombocytogram parameters in patients with ischemic stroke in the early recovery period.
Material and Methods. A clinical and laboratory analysis of 80 patients with acute noncardioembolic ischemic stroke in the early recovery period. Among those surveyed were 44 men and 36 women age (58.42±6.9) years. The control group consisted of 30 healthy individuals (16 men and 14 women) without severe somatic pathology and a history of cerebrovascular disorders, age (56.7 ± 4.8) years. Platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW), large platelet count (P-LCC) and large platelet percentage (P-LCC) were performed on an Abacus 30 hematology analyzer.
Results. Morphofunctional parameters of the platelet in patients with ischemic stroke are characterized by an increase in platelet size, platelet count, increase in the number and percentage of large platelets compared with the control group, indicating higher functional platelet activity, i.e increased aggregation capacity.
Conclusion: Indicators of MPV, PCT, P-LCC, P-LCR, can be considered as indicators of platelet activity in stroke in the early recovery period, which expands the possibilities of monitoring the effectiveness of antiplatelet therapy.
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