FUNCTIONAL STATE OF THE CARDIOVASCULAR SYSTEM ACCORDING TO THE RESULTS OF BICYCLE ERGOMETRY AND LIPID BLOOD COMPOSITION IN PATIENTS WITH STABLE CORONARY ARTERY DISEASE DEPENDING ON THE NUMBER OF AFFECTED CORONARY ARTERIES
DOI:
https://doi.org/10.11603/1811-2471.2019.v.i3.10529Keywords:
angina pectoris, coronary arteries, physical activity, lipids, obesityAbstract
SUMMARY. Ischemic heart disease (IHD) occupies a leading position in cardiac pathology. Prolonged myocardial ischemia is the cause of mortality and disability of the population, regardless of the socio-economic development of the country. The main proven risk factors for cardiovascular disease are hyper- and dyslipidemia and abdominal obesity.
The aim of the study – to analyze hemodynamic and ergometric parameters of the heart according to veloergometry (VEM) data, lipid composition of the blood and to evaluate anthropometric data in patients with stable coronary artery disease depending on the number of coronary arteries (CA) affected.
Material and Methods. The study involved 62 patients with stable coronary heart disease with functional angina (FC) III with heart failure (HF) IIА FC III with preserved left ventricular ejection fraction (LVEF). Among the surveyed men were dominated by 52 persons (83.9 %). The mean age of the patients was (61.2±1.2) years. Clinical groups are divided into subgroups depending on the number of affected CA: in 16 (25.8 %) patients according to the coronary angiography (CAG) revealed a single-vessel lesion, and in 46 (74.2 %) patients – a multi-vessel.
Results. Coronary and myocardial reserves and myocardial contractility according to VEM were shown to be reduced in both observation subgroups, however, such changes were observed in the case of two or more CA (p<0.05). According to anthropometric indices, body mass index (BMI) and waist circumference exceeded the normative value in 42 (67.7 %) patients (p<0.001), and in patients with multivascular CA the data of patients with the affected one CA (p<0.05) prevailed.
The amount of total cholesterol (TC), triglycerides (TG), low and high density lipoprotein cholesterol (LDL cholesterol, HDL cholesterol) in the serum were significantly different in both groups of patients (p<0.05).
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