INFERTILITY AS A MAJOR ASPECT OF IMPAIRED GENERATIVE FUNCTION OF WOMEN WITH NON-ATYPICAL ENDOMETRIAL HYPERPROLIFERATIVE PATHOLOGY
DOI:
https://doi.org/10.11603/1811-2471.2019.v.i3.10500Keywords:
infertility, hyperproliferative endometrial pathology, non-atypical endometrial hyperplasia, uterine body polypAbstract
SUMMARY. Female infertility in many countries of the world does not tend to decline. It is suggested that disorders of generative function may be associated with hyperproliferative endometrial pathology.
The aim – analysis of infertility indicators in women of Ukraine in 2010–2017 and in patients examined in the clinic with problems of endometrial hyperproliferation.
Materials and Methods. The data of the statistical reports of the Ministry of Healthcare of Ukraine and the State Statistics Service of Ukraine were used, as well as peculiarities of generative function in 184 examined patients with non-atypical endometrial hyperproliferative pathology (NAEHP), divided into 3 groups: I (n=60) – non-atypical endometrial hyperplasia (NAEH) (n=62) – uterine body polyps (UBP), III (n=62) – NAEH+UBP combination.
Results. The frequency of infertility among women in Ukraine was 4.07 %. Patients with NAEHP and secondary infertility with respect to existing pregnancies had a lower proportion of births, artificial abortions, and miscarriages compared to patients with NAEHP without a diagnosis of infertility. In 51.09 % of women with NAEHP, salpingitis was diagnosed, in 25.54 % – the adhesions of the pelvic organs, in 29.35 % – the primary infertility, in 16.30 % – the secondary. Salpingitis and adhesions among women with NAEHP were more common in patients with infertility than among those who did not have this diagnosis.
Conclusions. Removal of hyperplastically altered endometrial tissue followed by pathogenetic treatment should be the standard of care at the stage of pregravid preparation of such women.
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