ANALYSIS OF DIFFERENT CELL TECHNOLOGIES USE IN PRACTICAL DENTISTRY
DOI:
https://doi.org/10.11603/2415-8798.2018.1.8371Keywords:
cell engineering, reconstructive manipulation, dental practice.Abstract
The development of the modern implantology industry, which allows for the effective rehabilitation of dental patients in cases of partial and complete adentia, involves reducing the number of relative contraindications to the establishment of titanium intralesional structures, especially in cases of bone defect or insufficient geometric parameters of the residual crest.
The aim of the study – to analyze the results of cell engineering principles use in dental practice based on data from clinical, laboratory and experimental studies published in scientific periodical journals, and justify the need for systematization of different approaches to improve the efficiency of such manipulations during the reconstruction activities in maxillofacial area.
Materials and Methods. During the retrospective analysis of the literature 98 scientific publications were evaluated, of which 32 were represented in detailed manner as such that significantly differ or represent different qualitative approaches for reconstructive manipulation in dental practice. Primary data search was conducted using Google Scholar engine by keywords and formulation of search task based on individual words or phrases. The sample of relevant publications was formed using the method of content analysis, principles of which allowed us to systematize the results of research in the software Microsoft Excel 2013 (Microsoft Office, 2013).
Results and Discussion. The analysis of the principles of cell engineering in dental practice according to the clinical, laboratory and experimental research data suggests the complexity of the systematization for such type of results due to the different methodological approaches, different valuation parameters for initial and final results, and different purposes of a regeneratory therapy, that were used in previous studies. Some studies evaluated the actual recovery of a certain bone volume, but others just confirm the presence of existing regenerative potential.
Conclusions. Further development and modification of existing approaches for regenerative therapies with the use of third generation materials by Egusa (2012), enhances the effectiveness of various types of reconstructive surgery in maxillofacial area, and the lack of appropriate algorithms for stem cells management, their adequate collection and transfer remains questionable within regeneratory therapy in dental practice.
References
Hwang, D., & Wang, H.L. (2007). Medical contraindications to implant therapy: Part II : Relative contraindications. Implant dentistry, 16 (1), 13-23.
Misch, C.E. (1999). Endosteal implants for posterior single tooth replacement: alternatives, indications, contraindications, and limitations. Journal of Oral Implantology, 25 (2), 80-94.
Yamada, Y., Nakamura, S., Ito, K., Sugito, T., Yoshimi, R., Nagasaka, T., & Ueda, M. (2010). A feasibility of useful cell-based therapy by bone regeneration with deciduous tooth stem cells, dental pulp stem cells, or bone-marrow-derived mesenchymal stem cells for clinical study using tissue engineering technology. Tissue Engineering Part A, 16 (6), 1891-1900.
Yamada, Y., Nakamura, S., Ito, K., Kohgo, T., Hibi, H., Nagasaka, T., & Ueda, M. (2008). Injectable tissue-engineered bone using autogenous bone marrow–derived stromal cells for maxillary sinus augmentation: clinical application report from a 2–6-year follow-up. Tissue Engineering Part A, 14 (10), 1699-1707.
Yamada, Y., Ito, K., Nakamura, S., Ueda, M., & Nagasaka, T. (2011). Promising cell-based therapy for bone regeneration using stem cells from deciduous teeth, dental pulp, and bone marrow. Cell transplantation, 20 (7), 1003-1013.
Zizelmann, C., Schoen, R., Metzger, M.C., Schmelzeisen, R., Schramm, A., Dott, B., ... & Gellrich, N.C. (2007). Bone formation after sinus augmentation with engineered bone. Clinical oral implants research, 18 (1), 69-73.
Egusa, H., Sonoyama, W., Nishimura, M., Atsuta, I., & Akiyama, K. (2012). Stem cells in dentistry–part I: stem cell sources. Journal of prosthodontic research, 56 (3), 151-165.
Egusa, H., Sonoyama, W., Nishimura, M., Atsuta, I., & Akiyama, K. (2012). Stem cells in dentistry–Part II: Clinical applications. Journal of prosthodontic research, 56 (4), 229-248.
Bluteau, G., Luder, H.U., De Bari, C., & Mitsiadis, T.A. (2008). Stem cells for tooth engineering. Eur Cell Mater, 16 (1), 9.
Risbud, M. V., & Shapiro, I. M. (2005). Stem cells in craniofacial and dental tissue engineering. Orthodontics & craniofacial research, 8 (2), 54-59.
Huang, G.T. (2009). Pulp and dentin tissue engineering and regeneration: current progress. Regenerative medicine, 4 (5), 697-707.
Huang, G.T. J., Sonoyama, W., Chen, J., & Park, S.H. (2006). In vitro characterization of human dental pulp cells: various isolation methods and culturing environments. Cell and tissue research, 324 (2), 225.
Gonshor, A., McAllister, B.S., Wallace, S.S., & Prasad, H. (2011). Histologic and histomorphometric evaluation of an allograft stem cell-based matrix sinus augmentation procedure. International Journal of Oral & Maxillofacial Implants, 26 (1).
Shi, S., Robey, P.G., & Gronthos, S. (2001). Comparison of human dental pulp and bone marrow stromal stem cells by cDNA microarray analysis. Bone, 29 (6), 532-539.
Morsczeck, C., Schmalz, G., Reichert, T. E., Völlner, F., Galler, K., & Driemel, O. (2008). Somatic stem cells for regenerative dentistry. Clinical oral investigations, 12(2), 113-118.
de Mendonça Costa, A., Bueno, D.F., Martins, M.T., Kerkis, I., Kerkis, A., Fanganiello, R.D., Passos-Bueno, M.R. (2008). Reconstruction of large cranial defects in nonimmunosuppressed experimental design with human dental pulp stem cells. Journal of Craniofacial Surgery, 19 (1), 204-210.
Wei, X., Wu, L., Ling, J., Liu, L., Liu, S., Liu, W. & Xiao, Y. (2008). Differentially expressed protein profile of human dental pulp cells in the early process of odontoblast-like differentiation in vitro. Journal of endodontics, 34 (9), 1077-1084.
Kim, S.H., Kim, K. H., Seo, B.M., Koo, K.T., Kim, T.I., Seol, Y.J. & Lee, Y.M. (2009). Alveolar bone regeneration by transplantation of periodontal ligament stem cells and bone marrow stem cells in a canine peri-implant defect model: a pilot study. Journal of periodontology, 80 (11), 1815-1823.
Estrela, C., Alencar, A.H.G.D., Kitten, G.T., Vencio, E.F., & Gava, E. (2011). Mesenchymal stem cells in the dental tissues: perspectives for tissue regeneration. Brazilian dental journal, 22 (2), 91-98.
Schimming, R., & Schmelzeisen, R. (2004). Tissue-engineered bone for maxillary sinus augmentation. Journal of Oral and Maxillofacial Surgery, 62 (6), 724-729.
Riccio, M., Maraldi, T., Pisciotta, A., La Sala, G. B., Ferrari, A., Bruzzesi, G., De Pol, A. (2012). Fibroin scaffold repairs critical-size bone defects in vivo supported by human amniotic fluid and dental pulp stem cells. Tissue Engineering Part A, 18 (9-10), 1006-1013.
Shayesteh, Y.S., Khojasteh, A., Soleimani, M., Alikhasi, M., Khoshzaban, A., & Ahmadbeigi, N. (2008). Sinus augmentation using human mesenchymal stem cells loaded into a β-tricalcium phosphate/hydroxyapatite scaffold. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 106 (2), 203-209.
Matsubara, T., Suardita, K., Ishii, M., Sugiyama, M., Igarashi, A., Oda, R., Miyazaki, K. (2005). Alveolar bone marrow as a cell source for regenerative medicine: differences between alveolar and iliac bone marrow stromal cells. Journal of Bone and Mineral Research, 20 (3), 399-409.
Cerruti Filho, H., Kerkis, I., Kerkis, A., Tatsui, N.H., Da Costa Neves, A., Bueno, D. F., & Da Silva, M.C.P. (2007). Allogenous bone grafts improved by bone marrow stem cells and platelet growth factors: clinical case reports. Artificial organs, 31 (4), 268-273.
Srouji, S., Kizhner, T., David, D.B., Riminucci, M., Bianco, P., & Livne, E. (2009). The Schneiderian membrane contains osteoprogenitor cells: in vivo and in vitro study. Calcified tissue international, 84 (2), 138-145.
Mao, J.J., & Prockop, D.J. (2012). Stem cells in the face: tooth regeneration and beyond. Cell stem cell, 11 (3), 291-301.
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