RESULTS OF COMPLEX DIFFERENTIAL TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME
DOI:
https://doi.org/10.11603/2415-8798.2017.2.7838Keywords:
diabetic foot syndrome, complex treatment.Abstract
Diabetes mellitus (DM) worldwide has acquired pandemic proportions and the number of cases continues to rise permanently, which is one of the most important medical and socio-economic problems. The structure of late complications of diabetes; diabetic foot syndrome is a leader causing the increased morbidity and mortality in this group of patients. It complicates the course of diabetes in 4.6–25 % of patients, with an annual diagnosis of new lesions within 2.2–5.9 % of patients with diabetes.
The aim of the study – to evaluate the effectiveness of methods and developed complex pathogenetic differentiated treatment of diabetic foot syndrome.
Materials and Methods. The results of treatment of 1716 patients with the syndrome of diabetic foot were analyzed. On the basis of the features of the pathological process, microbiological, cytological and morphological studies, the study of central and peripheral hemodynamics of the lower limbs, x-ray survey developed objective criteria integrated differential treatment, and performance criteria for surgical treatments and minor amputations in the foot.
Results and Discussion. The research allowed to state that the formation of a differentiated approach to surgical treatment of purulent necrotic lesions of the lower extremities against diabetes should be considered pathogenic form of diabetic foot, depth and distribution of lesions, topographical location, natural flora inflammatory lesions, and indicators of peripheral hemodynamics of limbs. In order to preserve the lower extremity in the presence of reasonable evidence, preference should be given one-step radical debridement and small foot amputation.
Conclusions. Timely and proper use of differentiated pathogenesis of complex treatment regimens allow the diabetic foot syndrome quantitatively and qualitatively improve treatment above named diseases, resistance to save limbs and reduce the number of high amputations of the lower limbs to 9.6 %, and reduce the term inpatient treatment 5.8 ± 1.4 bed-days to improve the quality of life of patients and their social adaptation.
References
Suntsov, Yu.I., Bolotskaya, L.L., Maslova, O.V., & Kazakov, I.V. (2011). Epidemiologiya sakharnogo diabeta i prognoz ego rasprostraneniya v Rossiyskoy Federatsii [Epidemiology of diabetes mellitus and prognosis of its spread in the Russian Federation]. Sakharnyy diabet – Diabetes Mellitus, 1, (50), 15-19 [in Russian].
Maslova, O.V., & Suntsov, Yu.I. (2011). Epidemiologiya sakharnogo diabeta i mikrososudistykh oslozhneniy [Epidemiology of diabetes mellitus and microvascular complications]. Sakharnyy diabet – Diabetes Mellitus, (3), 6-11 [in Russian].
Shaw, J.E., Sicree, R.A., & Zimmet, P.Z. (2010). Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res. Clin. Pract., 1, (87), 4-14.
Donath, M.Y., & Shoelson, S.E. (2011). Type 2 diabetes as an inflammatory disease. Nat. Rev. Immunol., 2, 11, 98-107.
Dedov, I.I. (2012). Sakharnyy diabet – opasneyshyy vyzov mirovomu soobshchestvu [Diabetes mellitus is a dangerous challenge to the world community]. Vestnik RAMN – Bulletin of the Russian Academy of Medical Sciences, (1), 7-13.
Apelqvist, J., Bakker, K., & van Houtum, W.H. (2010). Practical guidelines on the management and prevention of the diabetic foot. Diabetes Metab. Res. Rev., 24, (1), 181-187.
Antsyferov, M.B. (2013). Sindrom diabeticheskoy stopy: diagnostika, lechenie i profilaktika [Diabetic foot syndrome: diagnosis, treatment and prevention]. Moscow: Meditsynskoe informatsyonnoe agentstvo [in Russian].
Dedov, I.I., & Shestakova, M.V. (2013). Algoritmy spetsyalizirovannoy meditsynskoy pomoshchi bolnym sakharnym diabetom [Algorithms for specialized medical care for patients with diabetes mellitus]. Moscow [in Russian].
Zahorodnii, O.V., & Fedorenko, V.P. (2009). Chastota velykoi amputatsii nyzhnikh kintsivok pry khirurhichnykh uskladnenniakh stopy khvorykh na tsukrovyi diabet [The frequency of large amputations of lower limb foot complications in surgical patients with diabetes]. Lvivskyi medychnyi chasopys – Lviv Medical Journal, (2), 85-88 [in Ukrainian].
Downloads
Additional Files
Published
How to Cite
Issue
Section
License
Authors who sent their manuscript to "Вісник наукових досліджень. Bulletin of Scientific Research" Surgery agree to the following terms:
a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)