CO–AMLESSA – EFFECTIVE ORGANOPROTECTIVE DRUG COMBINATION IN TREATING HYPERTENSION OF OLD PATIENTS WITH CO- AND POLYMORBID DISEASES

Authors

  • O. V. Davydovych P. Shupyk National Medical Academy of Postgraduate Education, Kyiv
  • L. A. Stadnyuk P. Shupyk National Medical Academy of Postgraduate Education, Kyiv
  • N. Ya. Davydovych P. Shupyk National Medical Academy of Postgraduate Education, Kyiv
  • V. O. Lykhatska I. Horbachevsky Ternopil State Medical University
  • I. I. Vyshnevetska I. Horbachevsky Ternopil State Medical University
  • I. V. Niku P. Shupyk National Medical Academy of Postgraduate Education, Kyiv
  • V. V. Yasenivka I. Horbachevsky Ternopil State Medical University

DOI:

https://doi.org/10.11603/2415-8798.2017.2.7812

Keywords:

hypertention, old age, Co-Amlessa, comorbidity.

Abstract

The main problem of hypertension treatment is an effective control of blood pressure (BP) ensuring, which should be kept up to 140/90 mm Hg. There are often combination of hypertension with other diseases (diabetes, podagra, chronic obstructive pulmonary disease, coronary heart disease and so on.) in older people, which requires an integrated assessment of human health and regard to interaction of drugs assigned.

The aim of the study – to learn published data about the effectiveness of drugs used to stabilize blood pressure in elderly patients with concomitant pathology.

Materials and Methods. The material serves the published data about treatment of hypertension in older age groups by several antihypertensive medications. Polimorbidity of such patients is caused by the universal trend of population aging, "rejuvenation" , increasing incidence of chronic diseases, rising of negative influence of different environmental factors (Dranhoy MG, 2007).

Results and Discussion. Advisability of combination antihypertensive drugs (diuretic + ACE inhibitor + calcium channel antagonist) in elderly patients with co- and polymorbidity was described.

Conclusions. Appointment of Сo-Amlessa for old patients with co- and polymorbidity manifested significant hypotensive effect, which is held during the day, accompanied by patronage organs–targets and manifests a high adherence of patients.

Author Biographies

O. V. Davydovych, P. Shupyk National Medical Academy of Postgraduate Education, Kyiv

заслужений працівник вищої освіти України, доцент кафедри терапії і геріатрії НМАПО ім. П.Л. Шупика

L. A. Stadnyuk, P. Shupyk National Medical Academy of Postgraduate Education, Kyiv

професор, завідувач кафедри терапії і геріатрії  НМАПО ім. П.Л. Шупика

N. Ya. Davydovych, P. Shupyk National Medical Academy of Postgraduate Education, Kyiv

доцент кафедри терапії і геріатрії НМАПО ім. П.Л. Шупика

V. O. Lykhatska, I. Horbachevsky Ternopil State Medical University

доцент кафедри ТДМУ ім. Горбачевського

I. I. Vyshnevetska, I. Horbachevsky Ternopil State Medical University

клінічний ординатор кафедри терапії і геріатрії НМАПО ім.П.Л.Шупика

I. V. Niku, P. Shupyk National Medical Academy of Postgraduate Education, Kyiv

клінічний ординатор кафедри терапії і геріатрії НМАПО ім.П.Л.Шупика

V. V. Yasenivka, I. Horbachevsky Ternopil State Medical University

лікар-інтерн кафедри терапії і геріатрії НМАПО ім. П.Л. Шупика

References

Davydovych, O.V., & Davydovych, N.Ya. (2007). Klinichna farmakolohiia ta farmakoterapiia v kardiolohii [Clinical pharmacology and pharmacotherapy in cardiology]. Ternopil: Pidruchnyky i pisibnyky [ in Ukrainian].

Drangoy, M.G. (2007). Vozrastnye bolezny [Age-related diseases]. Moskow: Eksmo [in Russian].

Kolomiets, M.Yu., & Vasheniak O.O.(2012). Komorbidnist i polimorbidnist u terapevtychnii praktytsi [Comorbidity and polymorbiity in therapeutic practice]. Ukrainskyi medychnyi chasopys – Ukrainian Medical Journal, 5, 140-143 [ in Ukrainian].

Komissarenko, I.A.(2009). Polimorbidnost i metabolicheskiy sindrom u pozhylykh [Polymorbidity and metabolic syndrome in elderly]. Klinicheskaya gerontologia – Clinical Gerontology, 15, 29-38 [in Russian].

Lazebnik, L.B. (2007). Starenie i polimorbidnost [Aging and polymorbidity]. Novosti meditsyny i farmatsyi – News of Medicine and Pharmacy, 1, 10-11 [in Russian].

Campbell-Scherer, D. Multi-morbidity: a challenge for evidence-based medicine. Evid. Based Med., 15 (6), 165-166.

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Published

2017-08-17

How to Cite

Davydovych, O. V., Stadnyuk, L. A., Davydovych, N. Y., Lykhatska, V. O., Vyshnevetska, I. I., Niku, I. V., & Yasenivka, V. V. (2017). CO–AMLESSA – EFFECTIVE ORGANOPROTECTIVE DRUG COMBINATION IN TREATING HYPERTENSION OF OLD PATIENTS WITH CO- AND POLYMORBID DISEASES. Bulletin of Scientific Research, (2). https://doi.org/10.11603/2415-8798.2017.2.7812

Issue

No. 2 (2017)

Section

EXCHANGE OF EXPERIENCE

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