PECULIARITIES OF GESTATION IN WOMEN WITH HYPERTENSIVE DISORDERS (RETROSPECTIVE ANALYSIS)
DOI:
https://doi.org/10.11603/2415-8798.2017.2.7742Keywords:
arterial hypertension in pregnant women, risk factors, preeclampsia.Abstract
Insufficient effectiveness of existing methods of treatment of hypertensive conditions during pregnancy justifies the expediency of searching for new antihypertensive agents and methods of their use in pregnant women, which will prevent the development of preeclampsia and eclampsia in a significant number of cases, and thus reduce the incidence of pregnancy complications and perinatal losses.
The aim of the study – to detect factors affecting the development of preeclampsia in pregnant women with various types of hypertensive disorders.
Materials and Methods. A retrospective analysis and a multidimensional development of 564 monitoring cards for pregnant women and women with hypertensive disorders was conducted.
Results and Discussion. Chronic hypertension in pregnancy should be considered as one of the risk factors for pre-eclampsia and preeclampsia combined, and low efficiency of antihypertensive therapy or lack of compliance can be considered a precursor to the development of these complications. The presence of untreated chronic hypertension and pre-eclampsia provokes demonstration combined preeclampsia in pregnant 2–3 weeks earlier than women without hypertension or at its adequate therapy.
Conclusions. The presence of not corrected chronic hypertension in pregnancy significantly increases the frequency of their late gestosis and significantly worsens the prognosis of pregnancy. Applying an adequate antihypertensive therapy vasodilator betablockers contributes significant reduction in the incidence of preeclampsia and the severity of its course.
References
Roberts, J.M. & Catov, J.M. (2012). Pregnancy is a screening test for later life cardiovascular disease: now what? Research recommendations / J. M. Roberts, Womens Health Issues, 22, 123–128.
Gifford, R.W., August, P.A. & Cunningham, G. (2000). Working Group on High Blood Pressure in Pregnancy. American Academy of Family Physicians. American Academy of Insurance Medicine. Retrieved from: http://www.vidyya.com/pdfs/1026preg.pdf
2013 ESH/ESC Guidelines for the management of arterial hypertension; “Hypertension in Pregnancy”; https://www.escardio.org/static_file/Escardio /Guidelines/publications/AHWeb_EM_Hypertension_2013.pdf
Nakaz MOZ Ukrainy vid 24.05.2012 No 384.
Cerdeira, A.S. & Karumanchi, S.A., Edelstein, C.L. (Eds.) (2011). Biomarkers in preeclampsia. Biomarkers of kidney disease. 1st ed. Amsterdam; Boston: Academic Press/Elsevier, 385–426.
Mellina, I.M., Hutman, L.B.,Tutchenko, L.I. & Hudymenko, A.A. (2011). Hipertonichna khvoroba u vahitnykh: udoskonalennia systemy orhanizatsiynykh I likuvalno-profilaktychnykh zakhodiv DU “Instytut pediatrii, akusherstva I hinekolohii AMN Ukrainy” [Hypertonic disease in pregnant women: improving the system of organizational and therapeutic and prophylactic measures. DU "Institute of Pediatrics, Obstetrics and Gynecology, Academy of Medical Sciences of Ukraine"]. Arterialna hipertenziia – Arterial hypertension, 1(15), 106–119.
Nahornaia, V.F. (2013). Hestozy [Gestosis]. Zdorovia Ukrainy. Tematychnyi vypusk “Akusherstvo I hinekolohiia” – Health of Ukraine. Thematic issue “Obstetrics and Gynecology”, 35–37.
“Hypertension in Pregnancy”, The American College of Obstetrician and Gynecologists, Task Force, 2013; http://www.acog.org/Resources-And-Publications/Task-Force-and-Work-Group-Reports/Hypertension-in-Pregnancy
Lowe, S.A., Lust, K., McMahon, L.P. (2014). The Society of Obstetric Medicine of Australia and New Zealand Guideline for the Management of Hypertensive Disorders of Pregnancy. Sydney. SOMANZ. https://somanz.org/documents/HTPregnancyGuidelineJuly2014.pdf
George, E.M. & Granger J.P. (2011). Endothelin: key mediator of hypertension in preeclampsia. Am. J. Hypertens, 24, 964–969.
Pidhirnyi, Ya.M. (2013). Anesteziia ta intensyvna terapiia u vahitnykh z preeklampsiieiu [Anesthesia and intensive care in pregnant women with preeclampsia / eclampsia]. Medytsyna nevidkladnykh staniv – Emergency medicine, 53, 19–26.
Downloads
Published
How to Cite
Issue
Section
License
Authors who sent their manuscript to "Вісник наукових досліджень. Bulletin of Scientific Research" Surgery agree to the following terms:
a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)