DYNAMICS OF INDICATORS OF ORAL FLUID AND CLINICAL CONDITION OF PERIODONTAL TISSUES IN CHILDREN WITH GINGIVITIS UNDER THE INFLUENCE OF THERAPEUTIC AND PROPHYLACTIC MEASURES
DOI:
https://doi.org/10.11603/2415-8798.2017.1.7517Keywords:
chronic gingivitis, antioxidant protection, children, treatment.Abstract
Given the high prevalence of periodontal inflammation in children of all ages the lack of effectiveness of preventive and therapeutic measures must be concluded.
The aim of the study – a comparative assessment of traditional treatment of gingivitis therapy using anti-inflammatory gel with neovitin.
Materials and Methods. 47 children with chronic catarrhal gingivitis were taken under medical supervision and divided into groups: basic (23 children) and comparison (24 children). All children held common therapy under the protocols of care – basic therapy. In the study group we used during the month of pathogenic orientation – an anti-inflammatory gel with neovitin recommended hygiene. In the comparison group for local therapy has been used 3 % solution of hydrogen peroxide; to rinse the mouth (during the first week of treatment) – "Rotokan" therapeutic and preventive toothpaste. Test review and examination of the definition hygienic state of oral hygiene index according to Yu. A. Fedorov and V. V. Volodkinа. It was received the prevalence and intensity of inflammation in the gums evaluated using samples Schiller-Pisarev and PMA index, indicators of oral fluid (content of total glutathione, oxidized and reduced glutathione, glutathione redox index).
Results and Discussion. After treatment liquidation process of gingivitis in patients of the group was accompanied by a decrease PMA index in 2.8 times; GE – 1.6 times. It was established the shortening the treatment of children in the application of the proposed medical scheme. After 0.5 years of total glutathione content in the study group was significantly more than the indicator relative to the treatment group (1.2 times) and of that of the comparative group through 0.5 years (1.2 times). Also true is the difference between the content of glutathione in children and the main comparative groups – 1.2 times, glutathione redox index in the study group increased significantly and even exceeded the control group.
Conclusion. The use of the proposed therapy using gel with neovitin contributed to a better treatment outcome, reduce the degree of gum disease, the number of visits to the doctor to the improvement of antioxidant protection in oral fluid of children, and, more six months after treatment.
References
Khomenko, L.A., Chaykovskyi, Yu.B. Savychuk, A.V. & Savychuk, N.O. (2007). Terapevticheskaya stomatologiya detskogo vozrasta [Therapeutic dentistry of childhood]. Kiev: Knyha plyus [in Russian].
Voskresenskyy, O.N., & Tkachenko, O.N. (1991). Rol perekysnoho okysleniya lipidov v patogeneze parodontita [Role of peroxide oxidation of lipids in the pathogenesis of periodontitis]. Stomatologiya – Stomatology, 4, 5-10 [in Ukrainian].
Bogdanova, V.O., Svirin, V.V., & Ardatskaya, M.D. (2009). Klinicheskie vozmozhnosti ispolzovaniya metabolitov mikroflory v dyagnostike i lechenii vospalytelnykh zabolevaniy parodonta [Clinical possibilities of using metabolites of microflora in the diagnosis and treatment of inflammatory periodontal diseases]. Stomatolohgiya dlya vsekh – Stomatology for All, 4, 46-50 [in Ukrainian].
Volchenko, N.V., & Sokolova, Y.Y. (2014). Vliyanie kompleksnoy profilaktiky na uroven byokhimicheskikh markerov vospaleniya i disbioza v slyune detey s raznym tipom shkolnogo obucheniya [The effect of complex prevention on the level of biochemical markers of inflammation and dysbiosis in the saliva of children with different types of schooling]. Visnyk stomatolohii – Journal of dentistry, 1, 66-69 [in Ukrainian].
Zmarko, Yu.K., & Avdyeyev, O.V. (2014). Stupin aktyvnosti kysloi fosfatazy pry eksperymentalnomu hinhiviti ta za yoho korektsii [The degree of acid phosphatase activity in experimental gingivitis and for its correction]. Zdobutky klinichnoi i eksperymentalnoi medytsyny – Achievements of Clinical and Experimental Medicine, 1 (20), 48-50 [in Ukrainian].
Zmarko, Yu.K., & Avdyeyev, O.V. (2014). Zminy aktyvnosti luzhnoi fosfatazy pry eksperymentalnomu hinhiviti ta za yoho korektsii [Changes of acis phosphatase activity in experimental gingivitis and at its correction]. Ukrainskyi medychnyi almanakh – Ukrainian Medical Almanac, 2, (17), 32-33 [in Ukrainian].
Khavinson, V.Kh., & Ryzhak, G.A. (2010). Peptidnaya reguliatsyya osnovnykh funktsiy organizma [Peptide regulation of the body's basic functions]. Vestnik Roszdravnadzora – Journal of Russian Healthcare, 6, 58-62 [in Russian].
Fedorov, Yu.A. & Volodkyna, V.V. (1971). Otsenka ochyshchayushchego deystviya zubnykh gigiyenicheskykh sredstv i kachestva ukhoda za polostyu rta [Evaluation of the cleaning effect of dental hygiene products and quality of oral care]. Terapevticheskaya i ortopedicheskaya stomatologiya – Therapeutic and Orthopedic Dentistry, 1, 117-119 [in Ukrainian].
Zabolotnyy, T.D., Borysenko, A.V. & Pupin, T.I. (2013). Zapalni zakhvoriuvannia parodonta [Inflammatory periodontal disease]. Lviv: HalDent [in Ukrainian].
Anderson, M.E. (1985). Determination of glutathione and glutathione disulfide in biological samples. Meth. Enzymol., 113, 548-555.
Griffith, O.W. (1980). Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal. Biochem., 106 (1), 207-212.
Downloads
Published
How to Cite
Issue
Section
License
Authors who sent their manuscript to "Вісник наукових досліджень. Bulletin of Scientific Research" Surgery agree to the following terms:
a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal. 
b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)
