THE FEATURES OF CHANGES OF IMMUNOLOGIC INDEXES IN CHILDREN WITH CHRONIC BRONCHITIS

Authors

  • A. M. Shamsyev Samarkand State Medical Institute, Uzbekistan Republic
  • SH. A. Yusupov Samarkand State Medical Institute, Uzbekistan Republic
  • L. A. Mukhamadyeva Samarkand State Medical Institute, Uzbekistan Republic
  • B. A. Yuldashev Samarkand State Medical Institute, Uzbekistan Republic

DOI:

https://doi.org/10.11603/2415-8798.2016.4.7138

Keywords:

children, chronic bronchitis, immune status.

Abstract

Aim of investigation was the assessment of the condition of the immune status of children with chronic bronchitis. Changes in the system of not only in cell, but also in humoral immunity have been noted in children with chronic bronchitis which are going to have one-directed immunological shifts characterizing T-cell immunodeficiency. The reliably decreased amount of leucocytes have determined in children with chronic bronchitis in the period of the disease exacerbation. Such indexes as relative and absolute amount of leucocytes have reliably decreased in the comparison with normal parameters. One of the basic indexes of the humoral immunity is immunoglobulins of the blood urea. Including in the chain of the immunologic reactions immunoglobulins have been played a significant role in the pathogenesis of chronic bronchitis. From the point of humoral immunity in children with chronic bronchitis it has been noted significant hypoglobuliemia, extremely increasing of IgM level in the comparison with the practically healthy children, the levels of IgA and IgG have increased mostly in the group of children of the preschool age.

References

Bubnova N. Y. Khronycheskye nespetsyfycheskye zabolevanyya lehkykh u detey // v kn. “Kletochnaya byolohyya lehkykh v norme y pry patolohyy” ; pod red. V. V. Erokhyna, L. K. Romanovoy. – M., 2000. – S. 351–357.

Huraryy N. Y. Kolychestvennyy analyz T- y V-lymfotsytov y ykh antyhen svyazyvayushchykh subpopulyatsyy u zdorovykh y bolʹnykh pnevmonyey detey : avtoref. dyss. na soyskanye uch. stepeny kand. med. nauk. / N. Y. Huraryy. – Samarkand, 1981. – 23 s.

Kalutsskyy P. V., Shvartskopf E. S., Okushko R. V. // Pedyatryya. – 2011. – T. 90, № 1. – S. 124–126.

Kapranov N. Y. Farmakoterapyya pry bronkholehochnykh porazhenyyakh u detey, bolʹnykh mukovystsydozom / N. Y. Kapranov // Rukovodstvo po farmakoterapyy v pedyatryy y det·skoy khyrurhyy. – M., 2002. – 267 s.

Kushelevskaya O. V. Chastota mykoplazmennoy y khlamydyynoy ynfektsyy u detey s vrozhdennymy porokamy razvytyya lehkykh y bronkhov / O. V. Kushelevskaya, Y. V. Zubkova, T. B. Sentsova // Voprosy sovr. pedyatryy. – 2006. – T. 5, № 1. – S. 321.

Latypova SH. A. Rolʹ NO-erhycheskoy systemy v formyrovanyy retsydyvyruyushchykh form bronkhytov u detey y pryntsypy ykh lechenyya : avtoref. dyss. kand. med. nauk. na soyskanye uch. stepeny / SH. A. Latypova. – Tashkent, 2011.

Paleev N. R. Khronycheskyy bronkhyt / N. R. Paleev, V. A. Ylʹchenko // Bolezny orhanov dykhanyya : v kn. “Rukovodstvo po vnutrennym boleznyam” ; pod red. N. R. Paleva. – M. : Medytsyna, 2000. – 287 s.

Rachynskyy S. V. Mesto khronycheskoy pnevmonyy y khronycheskoho bronkhyta v bronkholehochnoy patolohyy u detey / S. V. Rachynskyy, V. K. Tatochenko, Y. B. Volkov // Pedyatryya. – 2004. – № 1. – S. 58–66.

Rezolyutsyya konhressa KHIV konhressa Pedyatrov Rossyy s mezhdunarodnym uchastyem “Aktualʹnye problemy pedyatryy” // Rossyyskyy pedyatrycheskyy zhurnal. – 2010. – № 3. – S. 61/

Rozynova N. N. Trudnyy patsyent. Klynycheskye formy khronycheskykh vospalytelʹnykh zabolevanyy lëhkykh u detey: kryteryy dyahnostyky y pryntsypy terapyy / N. N. Rozynova. – ZH. Arkhyv. – № 10. – 2007.

Shamsyev F. M. Struktura zabolevaemosty orhanov dykhanyya v rehyonakh respublyky / F. M. Shamsyev, U. A. Karymov, N. D. Azyzova // Vestnyk vracha obshcheho profylya. Samarkand. – 2004. – № 4 (32). – S. 113–115.

Dombi V. H. Primary ciliarydyskinesia, immotilecilia syndrome, and Kartagener syndrome: diagnostic criteria / V. H. Dombi, H. Walt // Schweizerische Medizinisch Wochenschrift. J. Suisse de Med. – 1996. – Vol. 126. – P. 421–433.

Kitz R. Immunoglobulin levels in bronchoalveolar lavage fluid of children with chronic chest disease / R. Kitz // Pediat. Pulmon. – 2000.

Downloads

Published

2017-02-09

How to Cite

Shamsyev, A. M., Yusupov, S. A., Mukhamadyeva, L. A., & Yuldashev, B. A. (2017). THE FEATURES OF CHANGES OF IMMUNOLOGIC INDEXES IN CHILDREN WITH CHRONIC BRONCHITIS. Bulletin of Scientific Research, (4). https://doi.org/10.11603/2415-8798.2016.4.7138

Issue

No. 4 (2016)

Section

INTERNAL MEDICINE

License

Authors who sent their manuscript to "Вісник наукових досліджень. Bulletin of Scientific Research" Surgery agree to the following terms:

a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal. Результат пошуку зображень за запитом "CC-BY logo"         

b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.

c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)