ІМУНОЛОГІЧНІ АСПЕКТИ ГЕНЕРАЛІЗОВАНОГО ПАРОДОНТИТУ (ОГЛЯД ЛІТЕРАТУРИ)

N. M. Saveleva

doi:10.11603/2415-8798.2018.2.9122

Автор(и)

N. M. Saveleva Харківський національний медичний університет

DOI:

https://doi.org/10.11603/2415-8798.2018.2.9122

Ключові слова:

генералізований пародонтит, імунітет, імунологічні показники, соматичні захворювання.

Анотація

У статті викладено результати аналітичного огляду літературних даних в галузі оцінки стану імунологічних показників у пацієнтів із генералізованим пародонтитом. Наведені дані вказують на тісний зв’язок між станом імунної системи людини та розвитком генералізованого пародонтиту на тлі супутніх соматичних захворювань. Висвітлюється вплив пародонтопатогенних мікроорганізмів на імунну відповідь макроорганізму. Наводяться дані про стан місцевого та системного імунітету хворих на генералізований пародонтит, порушення в антитілоутворенні й функціонуванні клітинних механізмів захисту, активності та вміст в яснах і периферичній крові фагоцитуючих клітин, Т-лімфоцитів, природних кілерів, дисбаланс в цитокіновій системі. Ряд авторів відзначає значну роль у розвитку генералізованого пародонтита вторинного імунодефіциту, алергічних реакцій та аутоімунних процесів, загального стану адаптаційних механізмів організму. Розкриття або поглиблення знань про патогенез генералізованого пародонтиту дозволять побудувати оптимальну адекватну терапію і запропонувати ефективну профілактику стоматологічного захворювання.

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