Changes in oral liquid of preschool children with gingivitis under the influence of the therapeutic and preventive measures
DOI:
https://doi.org/10.11603/2311-9624.2018.2.8808Keywords:
3–5 year old children, chronic catarrhal gingivitis, non-specific protection, treatment.Abstract
Summary. The significant prevalence of inflammatory processes in periodontal tissues of children of different ages indicates insufficient effectiveness of preventive and therapeutic measures. Children of preschool age need special attention in the choice of therapeutic and prophylactic means.
The aim of the study – a comparative evaluation of traditional treatment of children aged from 3–5 years with chronic catarrhal gingivitis with therapy with the use of anti-inflammatory gel with neovitin.
Materials and Methods. 47 children with chronic catarrhal gingivitis were taken for dispensary observation and divided into groups: the main (23 children) and the comparative (24 children). All children underwent conventional therapy according to the protocols of medical care – basic therapy. In the main group, for a month, pathogenetic agents were used – an anti-inflammatory gel with neovitin, hygiene products were recommended. In the comparative group for local therapy, a 3 % hydrogen peroxide solution was used to rinse the oral cavity (during the first week of treatment) – Rotokan, a therapeutic and prophylactic toothpaste. Control examinations and examination with the definition of the hygienic state of the oral cavity using the hygienic index of Yu. A. Fedorov and V. V. Volodkina, the prevalence and intensity of the inflammatory process in the gums were assessed using the Schiller-Pisarev test and the PMA index, the oral fluid index (formation of oxyradical, urease activity, pH, viscosity, lysozyme content, degree of dysbiosis).
Results and Discussion. After the treatment, elimination of gum inflammation in patients of the main group was accompanied by a 2.8-fold decrease in the PMA index; GI – 1.6 times. The reduction in the period of treatment of children was revealed in the application of the proposed treatment regimen. The effectiveness of the treatment was confirmed by a decrease in the formation of oxyradicals immediately after treatment by 15.67 % and 10.98 % (p<0.05), a decrease in urease activity was observed in 8.43 % and 5.47 %; the viscosity of the oral fluid decreased by 54.51 % and 50.51 % (p<0.05), the incidence of dysbiosis decreased by 22.49 % (p<0.05) and 10.36 % in children of the primary and comparative groups, respectively. After 0.5 years, the lysozyme content in the oral fluid of children increased by 21.12 % and 7.09 % (p<0.05), the pH increased by 1.39 % and 0.25 % (p>0.05) in children of the primary and comparative groups, respectively.
Conclusions. The use of the proposed therapy with gel with neovitin contributed to the best results of treatment: a decrease in the degree of gingival inflammation by the PMA index by 2.8 times, a decrease in the number of visits to a doctor by 1.1, improvement of the oral fluid of children, and, to a greater extent, six months after the performed treatment.References
Avdieiev, O.V., Zmarko, Yu.K., Boikiv, A.B., & Drevnitska, R.O. (2017). Dynamika pokaznykiv rotovoi ridyny ta klinichnoho stanu tkanyn parodonta u ditei z hinhivitom pid vplyvom likuvalno-profilaktychnykh zakhodiv [Dynamics of indicators of oral liquid and clinical state of periodontal tissues in children with gingivitis under the influence of treatment and preventive measures]. Visnyk naukovykh doslidzhen – Journal of Scientific Researches, (1), 102-105 [in Ukrainian].
Avdieiev, O.V., Zmarko, Yu.K., Boikiv, A.B., & Drevnitska, R.O. (2017). Klinichna efektyvnist likuvalno-profilaktychnykh zakhodiv pry khronichnomu kataralnomu hinhiviti [Clinical efficacy of therapeutic and prophylactic measures in chronic catarrhal gingivitis]. Klinichna stomatolohiia – Clinical Dentistry, (2), 48-53 [in Ukrainian].
Volchenko, N.V., & Sokolova I.I. (2014). Vliyanie kompleksnoy profilaktiky na uroven bookhimicheskikh markerov vospaleniya i disbioza v slyune detey s raznym tipom shkolnogo obucheniya [Influence of complex preventive on the level of biochemical markers of inflammation and dysbiosis in saliva of children with different type of school education]. Visnyk stomatolohii – Journal of Stomatology, (1), 66-69 [in Ukrainian].
Fedorov, Yu.A. & Volodkina V.V. (1971). Otsenka ochishchayushchego deystviya zubnykh gigiyenicheskykh sredstv i kachestva ukhoda za polostyu rta [Assessment of cleaning effect of tooth hygienic means and quality of oral cavity care]. Terapevticheskaya i ortopedicheskaya stomatologiya. Kyiv: Zdorovia [in Russian].
Zmarko, Yu.K. & Avdieiev, O.V. (2014). Stupin aktyvnosti kysloi fosfatazy pry eksperymentalnomu hinhiviti ta za yoho korektsii [Activity level of acid phosphatase when experimental gingivitis and its correction]. Zdobutky klinichnoi i eksperymentalnoi medytsyny – Achievements of Clinical and Experimental Medicine, 1, (20), 48-50 [in Ukrainian].
Zmarko, Yu.K., & Avdieiev, O.V. (2014). Zminy aktyvnosti luzhnoi fosfatazy pry eksperymentalnomu hinhiviti ta za yoho korektsii [Changes of activity of alkaline phosphatase when experimental gingivitis and its correction]. Ukrainskyi medychnyi almanakh – Ukrainian Medical Almanac, 17, (2), 32-33 [in Ukrainian].
Khavinson, V.Kh. & Ryzhak, G.A. (2010). Peptidnaya regulyatsiya osnovnykh funktsiy organizma [Peptide regulation of the main body functions]. Vestnik Roszdravnadzora – Journal of Roszdravnadzor, 6, 58-62 [in Russian].
Khomenko, L.A., Chaykovskiy, Yu.B., Savichuk, A.V., & Savichuk, A.V. (2007). Terapevticheskaya stomatologiya detskogo vozrasta [Therapeutic dentistry of childhood]. Kyiv: Knyha plius [in Kussiar].
Zabolotnyi T.D., Borysenko, A.V., & Pupin T.I. (2013). Zapalni zakhvoriuvannia parodonta [Paradontium inflammatory diseases]. Lviv: HalDent [in Ukrainian].
Viarengo, A., Burlando, B., & Cavaletto, M. (1999). Role of metallothionein against oxidative stress in the mussel Mytilus galloprovincialis. Am. J. Physiol. Regul. Integr. Comp. Physiol. 277, R1612-R1619.
Shu., M., Morou-Bermudez, E., & Suárez-Pérez E. (2007). The relationship between dental caries status and dental plaque urease activity. Oral. Microbiology and Immunology, 22 (1), 61-66.
Dorofeychuk, V.G. (1968). Opredeleniye aktivnosti lizotsima nefelometricheskim metodom [Determination of lisolyne activity by nephelometric method]. Laboratornoye delo – Laboratory Case, 1, 28-30.
