Effect of combined therapy with the use of immunomodulators on cytokine status of patients with chronic generalized periodontitis I-II severity with enterobiasis
DOI:
https://doi.org/10.11603/2311-9624.2016.4.7230Keywords:
generalized chronic periodontitis, cytokines, enterobiasis.Abstract
There was conducted the study of clinical and immunological efficacy using of the two-stage scheme of complex treatment with immunomodulators in patients with chronic generalized periodontitis I–II degrees of severity on the background of enterobiosis it was shown that this therapy is pathogenetically justified, promotes more effective correction of cytokine status, normalizing the balance between pro-inflammatory and anti-inflammatory cytokines. The findings of the research data demonstrate a higher level of clinical and immunological effectiveness of the developed treatment compared with conventional therapy.
References
Samoylenko A. V. Sisteme v disbalans citokinov bolnyx generalizovannym parodontitom ya ego korrekciya citokinoterapiej / A. V. Samoylenko, I. S. Mashhenko, A. YU.. Makarevich / Sovremennaya stomatologiya. - 2001. - № 1. - S. 41-43.
Delaleu N. interleykina-1 beta i interleykina-18: regulirovaniye i deyatel'nost' v mestnoye vospaleniye /N. Delaleu, M. Bikkel' // Periodontol. - 2004. - Vol. 35. -P. 42-52.
Gmurman V. Ye. Teoriya veroyatnostey í matematicheskaya Statistika [Teoriya veroyatnostey i matematicheskaya statistika]. - Moskva, Vyssheye obrazovaniye, 2007. - R. 479.
Giganty S. Mediko-Biologicheskaya Statistika [Biomedical statistiki]. - Moskva, Izd-vo Praktika, 1999. - R. 459.
Lakin G. F. Biometriya [Biometriya]. - Moskva, Vysshaya shkola, 1990. - R. 352.