Changes of interleukin profile and level of immunoglobulins in rats with oral mucosa inflammatory diseases during different types of treatment

Authors

  • N. I. Mysula

DOI:

https://doi.org/10.11603/2311-9624.2015.3_4.6284

Abstract

The search for new approaches of treatment and prevention of diseases of the digestive system is still very important, as the prevalence of this pathology is increasing. The aim of our study was to compare the effectiveness of treatment of oral mucosa inflammatory diseases and explore the changes in the level of imunoglobulins and interleukins during treatment with rotokan, metrogyl denta and xenoderm. The analysis of the experiment data showed the positive correlation between the level of both proinflammatory and anti-inflammatory interleukins. Applied rotokan, metrogyl denta and xenoderm showed positive results, but their effectiveness was different. After the use of xenoderm, obtained data in most cases was not significantly different with the control group.

References

Elyzavetyna H. A. Syndrom funktsyonalnoi dyspepsyy v praktyke hastroenteroloha /

H. A. Elyzavetyna // Эffektyvnaia farmakoterapyia v hastroэnterolohyy y terapyy. – 2006. – № 1. –

S. 24–28.

Kotenko K. Yberohast – evropeiskye tra­dy­­­­tsyy na strazhe zdorovia / K. Kotenko // Zdo­rovia Ukrainy. – 2008. – № 10. – S. 51.

K voprosu o terapyy kyslotozavysymыkh zabolevanyi orhanov pyshchevarenyia u detei /

Y. L. Babyi, E. A. Kalashnykova, Y. N. Fedchuk,

V. Y. Velychko // Perynatolohyia y pedyatryia. – 2010. – № 1 (41). – S. 132–135.

Danylevskyi N. F. Parodontolohyia detskoho vozrasta / N. F. Danylevskyi, H. N. Vyshniak,

A. M. Polytun. – M. : Medytsyna, 1991. – 296 s.

Kolesova N. V. Osobennosty narushenyia barernoi funktsyy эpytelyia desnы pry heneralyzovannom parodontyte / N. V. Kolesova // Sovrem. stomatolohyia. – 2001. – № 3. – S. 42–44.

Komorbydnost boleznei parodonta y zhe­ludochno-kyshechnoho trakta / O. V. Eremyn,

A. V. Lepylyn, Y. V. Kozlova [y dr.] // Saratov. nauch.-med. zhurnal. – 2009. – T. 5, № 3. – S. 393–398.

Misula N. I. Avdeyev O V. Changes in the mucosa of the mouth when modeling gastroduodenitis animals /

N. I. Misula, O. V. Avdeyev // Journal of Health Sciences. – 2014. – Vol. 4. – № 11. – R. 33–40.

Published

2016-05-10

How to Cite

Mysula, N. I. (2016). Changes of interleukin profile and level of immunoglobulins in rats with oral mucosa inflammatory diseases during different types of treatment. CLINICAL DENTISTRY, (3_4). https://doi.org/10.11603/2311-9624.2015.3_4.6284

Issue

Section

Experimental researches