Modern ideas about the mechanism of regeneration of the lower jaw in conditions of polytrauma
DOI:
https://doi.org/10.11603/2311-9624.2015.1.6174Abstract
All pathological processes that occur in post-traumatic period directly affect subsequent healing tissues. Traumatic fractures of the facial skeleton represent a significant portion of all traumatic injuries of maxillofacial area. Regeneration process always involves processes of disintegration of damaged cells, formation of intercellular connections and adaptive adjustment regeneration. As a result of direct effects on bone of traumatic agent on periosteum cells undergo morphological and functional changes. Trauma causes bone poor circulation and loss of osteocytes, and significant enzymatic disorders. POL-AOP system plays an important role in the regeneration of bone tissue after crash and development of inflammatory complications. Thus, the correction of the pathogenesis has become an integral part of a comprehensive treatment of patients with fractures of the jaw bones.
References
Avrunyn A. S. Osteotsytarnoe remodelyrovanye: ystoryia voprosa, sovremennыe predstavlenyia y vozmozhnosty klynycheskoi otsenky / A. S. Avrunyn // Travmatolohyia y ortopedyia Rossyy. – 2012. – № 1 (63). – S. 128–134.
Bumeister V. I. Suchasnyi pohliad na reparatyvnyi osteohenez / V. I. Bumeister, M. V. Pohorelov // Svit medytsyny ta biolohii. – 2008. – № 4. – S. 104–110.
Vladymyrov Yu. A. Perekysnoe okyslenye lypydov v byolohycheskykh membranakh / Yu. A. Vladymyrov, A. Y. Archakov. – M. : Nauka, 1972. – 252 s.
Vlyianye mekhanyzma travmы na sostoianye peryostalnыkh ystochnykov osteoreparatsyy / [V. H. Klymovytskyi, V. M. Oksymets, V. Yu. Chernыsh y dr.] // Travma. – 2008. – T. 9, № 4. – S. 30–35.
Volotovska N. V. Osoboyvosti reaktsii peroksydnoho okysnennia lipidiv, antyoksydantnoho zakhystu, endohennoi intoksykatsii ta tsytolizu pid vplyvom travmy riznoho stupenia tiazhkosti / N. V. Volotovska, A. A. Hudyma // Zdobutky klinichnoi i eksperymentalnoi medytsyny. – 2012. – № 1. – S. 29–33.
Hololobov V. H. Skeletnыe tkany. Posttravmatycheskaia reheneratsyia // V. H. Hololobov. – Rukovodstvo po hystolohyy.– SPb.: SpetsLyt, 2001. – T. 1. – S. 328–336.
Horydova L. D. Nesrashchenyia plechevoi kosty (faktorы ryska) / L. D. Horydova, K. K. Romanenko // Ortoped., travmatol. – 2000. – № 3. – S. 72–76.
Hryhorovskyi V. V. Posttravmatycheskye porazhenyia kostei: patomorfolohyia y patohenez : dys. … d. med. nauk : 14.03.02 / V. V. Hryhorovskyi. – K., 2001. – 312 s.
Huminskyi Yu. Y. Suchasni aspekty ekomorfolohii reparatyvnoho osteohenezu / Yu. Y. Huminskyi, O. V. Korenkov // Visnyk SumDU. Seriia Medytsyna. – 2009. – T. 1, № 2. – S. 17–22.
Danylov R. K. Uchenye o hystoheneze y reheneratsyy tkanei: sovremennoe sostoianye y perspektyvы razvytyia / R. K. Danylov // Morfolohycheskye osnovы hystoheneza y reheneratsyy tkanei. – SPb. : VMedA, 2001. – S. 3-4.
Danylov R. K. Эksperymentalno-hystolohycheskyi analyz hystoheneza y reheneratsyy tkanei (nekotorыe ytohy XX v. y perspektyvы dalneishykh yssledovanyi) / R. K. Danylov, T. H. Borovaia, N.D. Klochkov // Morfolohyia – 2000. – Vыp. 4. – S. 7–16.
Dedukh N. V. Preparatы kaltsyt y vytamynы D3 v profylaktyke, lechenyy osteoporoza y osteoporotycheskykh perelomov / N. V. Dedukh // Ukrainskyi medychnyi almanakh. – 2005. – T. 8, № 2. – S. 44–48.
Dedukh N. V. Skeletnыe tkany / N. V. Dedukh, E. Ya. Pankov // V kn.: Rukovodstvo po hystolohyy. – SPb. : SpetsLyt, 2001. – T.1. – S. 284–327.
Yspolzovanye metoda profylometryy dlia kolychestvennoi kharakterystyky mykrorelefa peryostalnoi poverkhnosty kosty / Yu. Yu. Astakhov, A. A. Doktorov, Y. V. Matveichuk, Denysov-Nykolskyi Yu. Y. // V kn.: Byomedytsynskye tekhnolohyy. Trudы Nauch.-yssled. y uchebno-metod. Tsentra byo.-med. tekhnolohyi VYLAR. – M.,1999. – Vыp. 12. – S. 53–70.
Korzh N. A. Reparatyvnaia reheneratsyia kosty / A. A. Korzh, A. M. Belous, E. Ya. Pankov. – M. : Medytsyna, 1972. – 232 s.
Korzh N. A. Reparatyvnaia reheneratsyia kosty / A. A. Korzh, A. M. Belous, E. Ya. Pankov. – M. : Medytsyna, 1972. – 232 s.
Korzh N. A. Reparatyvnaia reheneratsyia kosty: sovremennыi vzghliad na problemu. Stadyy reheneratsyy / N. A. Korzh, N. V. Dedukh // Ortopedyia, travmatolohyia y protezyrovanye. – 2006. – № 1. – S. 76–84.
Korzh N. A. Reparatyvnaia reheneratsyia kosty: sovremennыi vzghliad na problemu. Lokalnыe faktorы, vlyiaiushchye na zazhyvlenye pereloma / N. A. Korzh, L.D. Horydova, K. K. Romanenko // Ortopedyia, travmatolohyia y protezyrovanye. – 2006. – № 2. – S. 99–105.
Kryvenko S. M. Patohenez poiednanoi ta mnozhynnoi kistiakovoi travmy oporno-rukhovoho aparatu / S. M. Kryvenko // Travma. – 2008. – T. 9, № 2. – S. 96–106.
Lavryshcheva P. Y. Morfolohycheskye y klynycheskye aspektы reparatyvnoi reheneratsyy opornыkh orhanov y tkanei / P. Y. Lavryshcheva, H. A. Onopryenko. – M. : Medytsyna, 1996. – 208 s.
Mineralnyi sklad kistky v rizni terminy reparatyvnoho protsesu / V. Z. Sikora, V. I. Bumeister, O. O. Ustianskyi // Zdobutky klinichnoi i eksperymentalnoi medytsyny. – 2007. – № 2. – S. 150–153.
Morfofunktsyonalnaia orhanyzatsyia reaktyvnost y reheneratsyia kostnoi tkany / [Hololobov V. H., Dulaev A. K., Deev R. V., Tsыhan E. N.]. – SPb. : Voenno-medytsynskaia akademyia, 2006. – 47 s.
Nahirnyi Ya. P. Vplyv hostroi travmy na ultrastrukturni zminy v klitynakh okistia u khvorykh z travmatychnymy perelomamy nyzhnoi shchelepy / Ya. P. Nahirnyi // Visnyk stomatolohii. – 2010. – № 4. – S. 66–68.
Onopryenko H.A. Vaskuliaryzatsyia kostei pry perelomakh y defektakh / H. A. Onopryenko. – M. : Medytsyna, 1995. – 224 s.
Osobennosty metabolyzma komponentov rehenerata kosty pry razlychnыkh uslovyiakh reparatyvnoho osteohenez / Kladchenko L. A., Horydova L. D., Malыshkyna S. V., Romanenko K. K. // Ukrainskyi medychnyi almanakh. – 2001. – T. 4, № 4. – S. 67–72.
Osobennosty metabolyzma komponentov rehenerata kosty pry razlychnыkh uslovyiakh reparatyvnoho osteohenez / L. A. Kladchenko, L. D. Horydova, S. V. Malыshkyna, K. K. Romanenko // Ukrainskyi medychnyi almanakh. – 2001. – T. 4, № 4. – S. 67–72.
Otsenka pokazatelei reparatyvnoho osteoheneza nyzhnei cheliusty y krыla podvzdoshnoi kosty u cheloveka / V. S. Astakhova, V. A. Malanchuk, L. M. Panchenko, O. L. Tsylenko // Ukrainskyi medychnyi chasopys. – 2002. – № 3. (29). – S. 136–141.
Pohranychna Kh. R. Struktura travmatychnykh poshkodzhen shchelepno-lytsevoi dilianky: statystychni tendentsii / Kh. R. Pohranychna, I. S. Sorokivskyi // Praktychna medytsyna. – 2009. – T. 15, № 4. – S. 43–47.
Popsuishapka A. K. Sroshchenye otlomkov posle pereloma kosty / A. K. Popsuishapka, V. A. Lytvyshko, O. A. Podhaiskaia // Mezhdunarodnыi medytsynskyi zhurnal. – 2009. – № 2. – S. 73–80.
Porushennia protsesiv reparatyvnoho osteohenezu pry diafizarnykh perelomakh dovhykh kistok (chynnyky ryzyku, diahnostyka, likuvalna taktyka) / M. O. Korzh, L. D. Horydova, K. K. Romanenko, V. I. Tarasenko // Travma. – 2005. – T.6, № 2. – S. 134–139.
Sydorkyna A. N. Byokhymycheskye aspektы travmatycheskoi bolezny y ee oslozhnenyi / A. N. Sydorkyna, V. H. Sydorkyn. – N. Novhorod : NNYYTO, 2007. – 120 s.
Stupnytskyi R. N. Stan protsesiv kistkovoho metabolizmu v osib z riznoiu shchilnistiu kistkovoi tkanyny alveoliarnykh vidrostkiv / R. N. Stupnytskyi // Ukrainskyi stomatolohichnyi almanakh. – 2008. – № 1. – S. 4–6.
Urovny orhanyzatsyy mineralnoho matryksa kostnoi tkany y mekhanyzmы, opredeliaiushchye parametrы ykh formyrovanyia / A. S. Avrunyn, P. M. Tykhylov, A. B. Abopyn, Y. H. Shcherbak // Morfolohyia. – 2005. – T. 127, № 2. – S. 78–82.
Otmar L. Polytrauma: pathophysiology, priorities, and management / L. Otmar // Trentz. – 2000 – P. 661–673.
Altered fracture repair in the absence of MMP9 / O. Colnot, Z. Thompson, Miclau T. [et al.] // Development. – 2003. – Vol. 120. – P. 4123–4133.
Amit S. Mistry Tissue Engineering Strategies for Bone Regeneration / Mistry Amit S., Mikos Antonios G. // Adv. Biochem. Engin. Biotechnol. – 2005. – № 94. – P. 2.
Augat P. Mechanics and mechnobiology of fracture healing in normal and osteoporotic bone / P. Augat, U. Simon, A. Liedert // Osteoporos. lnt. – 2005. – Vol. 16. – P. 36–43.
Carmouche J. J. Lead exposure inhibits fracture healing and is associated with increased chondrogenesis. delay in cartilage mineralization, and a decrease in osteoprogenitor frequency / J. J. Carmouche, J. E. Puzas, X. Zhang // Environmental Health Perspectives. – 2005. – Vol. 113, № 6. – P. 749–755.
Carter D. R. Mechanobiology of skeletal regeneration / D. R. Carter // CIin. Orthop. – 1998. – № 355, Suppl. – P. 541–555.
Cycioxygenase-2 regulates mesenchymal ceil differentiation into the osteoblast lineage and is critically involved in bone repair / X. Zhang, E. Schwarz, D. Young et al.] // J. Clin. Lnvest. – 2002. – Vol. 109. – P. 1405–1415.
Defective extracellular matrix reorganization by chronic wound fibroblasts is associated with alterations in TIMP-1, TIMP-2, and MMP-2 activity / H. Cook, K. J. Davies, K. G. Harding [et al.] // J. Invest. Dermatol. – 2000. – Vol. 115. – P. 225–233.
Ex vivo expansion and subsequent Infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor ceils): implications for therapeutic use / H. M. Lazarus, S. E. Haynesworth, S. L. Gerson [et al.] // Bone Marrow. Transplant. – 1995. – Vol. 16. – P. 557–564.
Sandor G. K. B. Bone Regeneration of the Craniomaxillofacial and Dento-alveolar Skeletons in the Framework of Tissue Engineering / G. K. B. S?ndor, T. C. Lindholm, C. M. L. Clokie // II Bone. – 2003. – P. 1–46.
Gene expression in older rats with delayed union of femoral fracture / R. A. Meyer, M. H. Meyer, M. Tenholder [et al.] // J. Bone Jt. Surg. – 2003. – Vol. 85-A. – P. 1243–1254.
Local tissue properties in bone healing: influence of size and stability of the osteotomy gap / P. Augat, K. Margevicius, J. Simon [et al.] // J. Orthop. Res. – 1998. – Vol. 16. – P. 475–481.
Mackenzie T. C. Human mesenchymal stem cells: insights from a surrogate in vivo assaysystem / T. C. Mackenzie, A. W. Flake // Cells Tissues Organs. – 2002. – Vol. 171., № 1. – P. 90–95.
Webb J. S. J. A review of fracture healing/ 280. / J. S. J. Webb, J. A. Tricker // Current Ortopaedics. – 2000. – Vol. 14. – P. 457–463.
