GANGES OF IMMUNE SYSTEM DURING PREGNANCY AT PATIENTS WITH MISCARRIAGE ON BACKGROUND HERPETICAL INFECTIONS
DOI:
https://doi.org/10.11603/24116-4944.2008.2.9536Keywords:
miscarriage of pregnancy, herpetical infection, immune status, proteflazidAbstract
On the basis of immunologic studies the author revealed that pregnant women with miscarriage against the background of herpes-viral infection are marked to have changes of the immune status by secondary immunodeficiency. It is established that carrying out of differentiated pregravida preparations with inclusion of protefazide and geviran with correction during pregnancy with protefazide in patients with miscarriage against the background of herpetic infection is pathogenetically proved, promotes correction of the function of the immune system: increase of the general number of Т- and B-lymphocytes, increase of the immunoregulation index CD4/CD8, reduction of CIC concentration, reduction of intensity of virus replication and reduction of the level of antigenic loading, influences positively on the course of pregnancy, promotes reduction in recurrence of herpetic infection, frequencies of threatening miscarriage, placentary dysfunction, premature birth and total perinatal losses.
References
Obstetric and perinatal problems TORCH -infections / Edited by Z.M. Dubossary, A.Ya. Saint-Chukka - Kyiv: Goal, 2003. - P. 89-112.
Vdovichenko Yu.P., Glazkov I.S., Kyashko G.P. Role violations of the immune system in the formation of obstetric and perinatal complications / Perinatology and pediatrics. - 2000. - No. 3. P. 14-18.
Markov I.S. Combination therapy is chronic recurrent herpes simplex virus (HSV) infection // Health of a woman. - 2001. - No. 3 (7). - Р. 5766.
Pisareva S.P., Tolkach S.M. Herpetic infection in pregnant women // Health of a woman. -2003 - No. 1 (13). - P. 66-69.
Sidelnikova V.М. The usual loss of pregnancy. - M .: Triada-X, 2005. - 304 p.
Chaika V.K., Dumina T.N. Missing pregnancy: Problems and treatment tactics / 3rd ed., revised and supplemented. - Nord Press LLC 2006 - 321 p.
Shemyakina N.N. Differentiated Approach to evaluation of the general immunological status of pregnant women with recurrent genital herpes // Collection of scientific works. Association of Obstetricians and Gynecologists Of Ukraine. - K.: Intermed, 2005. - Р. 447-450.
Bijko M., Sulovic V., Zivanovic V. Herpes simplex virus infection in a woman with a previous spontaneous abortion. J. Perinat Med. - 1990 – Р. 16, 7, 193-196.
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