CURRENT ASPECTS OFTHE BRONCHOPULMONARY DYSPLASIA PROBLEM IN PRETERM NEWBORNS

Authors

  • D. O. Dobrianskyi
  • O. P. Borysiuk
  • Z. V. Salabai

DOI:

https://doi.org/10.11603/24116-4944.2018.1.9467

Keywords:

bronchopulmonary dysplasia, definition, consequences, pathogenetic mechanisms, prevention, treatment, prematurity

Abstract

Bronchopulmonary dysplasia remains important cause of morbidity of very premature infants significantly affecting their long-term outcomes. Despite the all developments and latest advances in perinatal medicine the incidence of BPD has not decreased much during the last decades. Significant changes in BPD definition, pathology, pathophysiology, clinical course, radiological findings and management have occurred over the last 40 years. After many years of intensive and extensive investigations aimed to study mechanisms of BPD development and elaborate effective methods of its prevention and treatment, there is a discouraging paucity of proven safe and beneficial therapies to prevent or limit the severity of BPD. Additional researches are needed to fully understand the pathogenesis of BPD and develop improved interventions in the prevention and management of the condition.

References

1. Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely lowbirthweight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms / B. Schmidt, E.V. Asztalos, R.S. Robertsetal.//JAMA. - 2003. -V.289. - P.1124-1129.
2. Watts J.L., Saigal S. Outcome of extreme prematurity: as information increases so do the dilemmas // Arch. Dis. Child. Fetal Neonatal Ed. - 2006. - V. 91. - P. 221-225.
3. Ho S., Saigal S. Current survival and early outcomes of infants of borderline viability // NeoReviews. - 2005. - V.6. - P.123-132.
4. Northway W.H., Rosan R.C., Porter D.Y. Pulmonary disease following respiratory therapy of hyaline-membrane disease: bronchopulmonary dysplasia // N. Engl. J. Med. - 1967. -V.276. - P.357-368
5. Charafeddine L., D’Angio C.T., Phelps D.L. Atypical chronic lung disease patterns in neonates // Pediatrics. - 1999.-V.103.-P.759-765.
6. Jobe A.H. The new BPD // NeoReviews. - 2006. - V.7. - P.531-538.
7. Safety, reliability, and validity of a physiologic definition of bronchopulmonary dysplasia / M.C. Walsh, D. Wilson- Costello, A. Zadell et al. // J. Perinatol. - 2003. - V.23. - P.451-456.
8. The Official Statement of the American Thoracic Society as approved by the ATS Board of Directors, December 2002. Statement on the care of the child with chronic lung disease of infancy and childhood //Am. J. Respir. Crit. Care Med. - 2003.-V.168.-P.356-396.
9. Jobe A.H., Bancalari E. Bronchopulmonary dysplasia// Am. J. Respir. Crit. Care Med. - 2001. - V.163. - P.1723-1729
10. Ryan R.M. A new look at bronchopulmonary dysplasia classification //J. Perinat. - 2006. - V.26. - P. 207-209
11. NICHD Neonatal Research Network. Trends in neonatal morbidity and mortality for very low birthweight infants / A.A. Fanaroff, B.J. Stoll, L.L. Wright et al. //Am. J. Obstet. Gynecol. - 2007. - V.196. - P.1471-1478.
12. Kinsella J.P., Greenough A., Abman S.H. Bronchopulmonary dysplasia // Lancet. - 2006. - V. 367. - P.1421-1431.
13. Thomas W., Speer C.P. Prevention and treatment of bronchopulmonary dysplasia: current status and future prospects // J. Perinat. - 2007. - V.27. - Р.26-S32.
14. Darlow B.A., Graham P.J. Vitamin A supplementation for preventing morbidity and mortality in very low birthweight infants // Cochrane Database Syst. Rev. - 2002:CD000501.
15. NICHD Neonatal Network. A cluster-randomized trial of benchmarking and multimodal quality improvement to improve survival free of bronchopulmonary dysplasia in infants less than 1250 grams birth weight / M. Walsh, A. Laptook, S.N. Kazzi, W.A. Engle//Pediatrics. - 2007.-V.119. P.876-890.
16. Polin R.A., Sahni R. Newer experience with CPAP // Semin. Neonatol. - 2002. - V.7. - P.379-389.
17. Elective high frequency oscillatory ventilation versus conventional ventilation for acute pulmonary dysfunction in preterm infants / D.J. Henderson-Smart, T. Bhuta, F. Cools, M. Offringa // Cochrane Database Syst. Rev. - 2003: CD000104.
18. Bhuta T., Henderson-Smart D.J. Elective high frequency jet ventilation versus conventional ventilation for respiratory distress syndrome in preterm infants // Cochrane Database Syst. Rev. - 2000:CD000328.
19. McCallion N., Davis P.G., MorleyC.J. Volume-targeted versus pressure-limited ventilation in the neonate // Cochrane Database Syst. Rev. - 2005:CD003666.
20. Kinsella J.P., Abman S.H. Inhaled nitric oxide in the premature newborn //J. Pediatr. - 2007. - V.151. - P.10-15.
21. The STOP-ROP Multicenter Study Group. Supplemental therapeutic oxygen for prethreshold retinopathy of prematurity (STOP-ROP), a randomized, controlled trial, I: primary outcomes // Pediatrics. - 2000. - V.105. - P.295-310.
22. Oxygen-saturation targets and outcomes in extremely preterm infants / L.M. Askie, D.J. Henderson- Smart, L. Irwig, J.M. Simpson // N. Engl. J. Med. - 2003. - V.349. - P.959-967.
23. Bevilacqua G., Breart G., Gardini F. Mortality, severe respiratory distress syndrome, and chronic lung disease of the newborn are reduced more after prophylactic than after therapeutic administration of the surfactant Curosurf / J. Egberts, R. Brand, H. Walti et al. // Pediatrics. - 1997. - V.100. - P.4-10.
24. Inhaled versus systemic corticosteroids for the treatment of chronic lung disease in ventilated very low birth weight preterm infants / S.S. Shah, A. Ohlsson, H. Halliday, V.S. Shah // Cochrane Database Syst. Rev. - 2003: CD002057.
25. Prophylaxis against early adrenal insufficiency to prevent chronic lung disease in premature infants / K.L. Watterberg, J.S. Gerdes, K.L. Gifford, H.M. Lin //Pediatrics. - 1999. - V.104. - P.1258-1263.
26. Shah P, Ohlsson A. Alpha-1-proteinase inhibitor (a1PI) for preventing chronic lung disease in preterm infants // Cochrane Database Syst. Rev. - 2001 :CD002775.
27. Pulmonary outcome at 1 year corrected age in premature infants treated at birth with recombinant human CuZn superoxide dismutase / J.M. Davis, R.B. Parad, T. Michele etal. // Pediatrics. - 2003. - V.111. - P.469-476.
28. N-acetylcysteine administration during the first week of life does not improve lung function in extremely low birth weight infants / K. Sandberg, V. Fellman, L. Stigson et al. // Biol. Neonate. - 2004. - V.86. - P.275-279.
29. Caffeine therapy for apnea of prematurity / B. Schmidt, R.S. Roberts, P. Davis et al. // N. Engl. J. Med. - 2006. -V.354. - P.2112-2121.

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Published

2018-10-22

How to Cite

Dobrianskyi, D. O., Borysiuk, O. P., & Salabai, Z. V. (2018). CURRENT ASPECTS OFTHE BRONCHOPULMONARY DYSPLASIA PROBLEM IN PRETERM NEWBORNS. Actual Problems of Pediatrics, Obstetrics and Gynecology, (1). https://doi.org/10.11603/24116-4944.2018.1.9467

Issue

No. 1 (2008)

Section

PEDIATRICS

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