RISK FACTORS FOR OSTEOPOROSIS IN WOMEN WITH ARTERIAL HYPERTENSION AND OBESITY, WORKING UNDER UNFAVORABLE PRODUCTION CONDITIONS
DOI:
https://doi.org/10.11603/24116-4944.2018.2.8939Keywords:
postmenopausal period, osteoporosis, arterial hypertension, obesity, unfavorable conditions of productionAbstract
The aim of the study – to learn the risk factors for the development of osteoporosis in women with arterial hypertension and obesity, working in unfavorable production conditions for the prediction and early diagnosis of osteoporosis.
Materials and Methods. There were examined 110 women (mean age 56.2±1.74 years) in postmenopausal period (duration of postmenopause – (6.8±1.9) years). The main group consisted of 80 women with arterial hypertension stage 2 and obesity, who work under the influence of unfavorable factors of production. The control group consisted of 30 practically healthy women. Objective examination, anthropometry, ultrasonic densitometry was carried out. The main risk factors were studied using specially designed questionnaires.
Results and Discussion. The women of the main group demonstrated lower T-test indices (p˂0.05) compared to the control group, which indicates negative effect of unfavorable factors of production on the bone tissue condition and depends on the work experience. The correlation analysis of the main risk factors for osteoporosis and the T-test showed a statistically significant negative feedback between the T-test and unfavorable production factors (r = -0.456, p˂0.001), T-test and work experience under unfavorable production conditions (r = -0.724, p0.001), the T-test and the duration of postmenopause (r = -0.543, p˂0.001), the T-test and duration of arterial hypertension (r = -0.531, p˂0.001), T-test and body mass index (r = -0.592, p˂0.001) and indicates that hypertension, obesity, postmenopause and unfavorable factors of production have summing a negative impact on bone mineral density in female workers.
Conclusions. For the prediction and early diagnosis of osteoporosis, it is necessary to analyze all risk factors for the development of structural and functional changes in bone tissue. This will allow for timely treatment and prevention in the pre-clinical stage of the disease, reduce the risk of fractures and improve the quality of life.
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