CLINICAL EVALUATION OF THE EFFICACY OF HERBAL LICORICE ROOT AND ELECASOLUM IN THE TREATMENT OF ORAL LESIONS IN CHILDREN WITH INFLUENZA AND OTHER ACUTE RESPIRATORY VIRAL INFECTIONS
DOI:
https://doi.org/10.11603/24116-4944.2018.1.8441Keywords:
acute respiratory viral infections, oral lesions, herbal remedies licorice root, children.Abstract
The aim of the study – to optimize the treatment plan of local manifestations of the disease in oral cavity mucous membrane in complex therapy of children with acute respiratory viral infections with the use of herbal medicinal products of licorice root and elecasolum.
Materials and Methods. A clinical trial and treatment of 318 children with acute respiratory infections with manifestations of the disease in the oral cavity was conducted. Observed patients were divided into 2 groups: the first included 127 children, in the complex treatment of which we used licorice root herbal medicinal product and elecasolum for general and local treatment, the second – 132 patients received standard treatment. The efficiancy of the treatment was confirmed by laboratory tests.
Results and Discussion. In patients who received herbal medicinal product liquorice and elecasolum in a complex treatment, there was a tendency to reduce the general intoxication syndrome, shortening of the temperature reaction, duration of coughing. The hyperemia of mucous membrane in oral cavity disappeared with the use of proposed method of treatment on (2.06±0.05) days earlier than with the traditional one. Duration of catarrhal gingivitis decreased from (11.01±0.03) to (9.21±0.01) days, granular enanthema was changed by injection of blood vessels for (2.06±0.05) in children of the main group and (3.12±0.08) days in children of the group of comparison. The decrease in the intensity of the enhanced vascular pattern was observed for (7.68±0.02) days and (8.06±0.04) days, while the hemorrhagic spots were for (7.21±0.01) and (7.68±0.02) days in the children of the main group and comparison group. Erosions on mucous membrane were epithelized with the proposed treatment plan in (2.89±0.01) days faster, the duration of epithelization of the centers of desquamation of the epithelium of the tongue took 10.68±0.04 days (in the comparison group – (12.99±0.01) days). The intensity of the pain syndrome decreased in 24.41 % of patients. Regression of signs of acute viral sialadenitis were established (an average of 2.32±0.01) days less than that of the patients in the comparison group). The duration of regional lymphadenitis was reduced to (2.10±0.01) days and amounted to (11.11±0.03) days.
Conclusion. Monitoring of the effectiveness of the use of herbal licorice root and elecasolum herbal remedies in the complex treatment of children with acute respiratory viral infections with manifestations in oral cavity showed that the use of licorice root solution and elecasolum intraoraly and the local use of drugs in the form of irrigation and appliqués contributes to reducing of the disease duration.
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