EXPERIENCE OF CHOLECALCIFEROL IN THE TREATMENT OF ALLERGIC RHINITIS IN CHILDREN.
DOI:
https://doi.org/10.11603/24116-4944.2016.2.6835Keywords:
children, allergic rhinitis, vitamin D, treatment.Abstract
The aim of our study was to evaluate the efficacy of vitamin D3 in the treatment of allergic rhinitis in children. Under our supervision there were 34 children with allergic rhinitis, which determined the level of 25(OH)D in the serum at different dosing regimens сholecalciferol. The output level of 25(OH)D in the serum of children with AR was 26.91 ng/ml (Me=26.91; Q1=18.23; Q3=28.91), after the drug at a dose of vitamin D3 per day in 2000 IU 2 months – 37.56 ng/ml (Me=37.56; Q1=27.78; Q3=42.35), after the summer season (without taking cholecalciferol) – 38.12 ng/ml (Me=38.12; Q1=34.26; Q3=44.79) and after administration of high doses of cholecalciferol (4000 IU daily during remission and 5,000 IU daily during exacerbation rate 2 months) – 48.35 ng/ml (Me=48.35; Q1=43.67; Q3=62,78). Children with allergic rhinitis after application of high doses of vitamin D3 cholecalciferol reception was recommended year round, except for the summer months, the maintenance dose – 1000 IU daily and an exacerbation of the disease is recommended to increase the dose of 2.000 IU daily. Patients were under our supervision for 1 – 1.5 years. When assessing the clinical course of allergic rhinitis in children was noted alleviation of the disease, indicating the feasibility of cholecalciferol children with AR year round, except for the summer months.References
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