ROLE OF IMMUNOHISTOCHEMICAL STUDIES TO CLARIFY THE ETIOLOGICAL FACTORS OF RECURRENCE OF GENITAL PROLAPSE.
DOI:
https://doi.org/10.11603/24116-4944.2014.1.6637Abstract
Decrease in the ievei of estrogen hormones at menopause ieadsto atrophic changes in the tissues of the urinary tract and reduces eiasticity of tissues, which contributes to the deveiopment of genitai proiapse. It was found out that patients with recurrent genitai proiapse has a reduction in the expression of estrogen receptors in the epitheiium of the mucous iayer of the waii of the vagina and fasciaiiigamentapparatus of sexuai organs. The decrease of expression of estrogen receptors in the iining of the vagina by 76,2 %, in stroma-ЗІ ,5 % was estabiished. A direct correiation between the decrease of the ievei of ER in the iining of the vagina with a reduction in ER after thecardinai iigamentof the uterus was estabiiched.
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