EVALUATION OF SPECIFIC PROTEINS PREGNANCY AND DYNAMICS OF THEIR LEVEL IN THE BLOOD SERUM OF PREGNANT WOMEN WITH LOCAL NON- PROGRESSIVE DETACHMENT OF THE PLACENTA AND CHORION
DOI:
https://doi.org/10.11603/24116-4944.2016.1.6000Keywords:
pregnancy specific proteins, a local non- progressive detachment of the placenta, placental dysfunction.Abstract
There are reports about some diagnostic value of specific proteins placenta as maternal and fetal part, allowing comprehensively assess the relationship of fetoplacental complex. It surveyed 120 women with placental abruption episodes in the history of diagnosed or rhetrohorion and rhetroplacental hematoms at this gestation who were in the group at risk of miscarriage. The control group consisted of 30 women with uncomplicated pregnancy. Evaluated the levels of specific proteins pregnancy (free estriol, hCG and PAPP-A) in the serum of patients with physiological pregnancy and pregnancy is complicated by local non- progressive detachment of the placenta and chorionic and their fluctuations during the first half of gestational period. As for the protein concentration pregnancy PAPP-A in the blood of pregnant women studied groups, it should be noted in terms of 8–9 weeks of pregnancy in 48.5% of patients improving its content almost doubled compared with controls. The results allow to interpret that physiological pregnancy inherent unidirectional change data markers: low concentrations of PAPP-A correspond to low levels of β-hCG, while high levels of PAPP-A, accompanied by a high content of β-hCG Only multidirectional changes, primarily PAPP-A and β-hCG, is difficult to predict pregnancy.
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