ANTIOXIDANT DEFENSE SYSTEM OF THE NEWBORNS’ ORGANISM WITH FUNCTIONAL CARDIOVASCULAR SYSTEM DISORDER ON THE BACKGROUND PERYNATAL PATHOLOGY

Authors

  • Yu. D. Hodovanets
  • A. I. Peryzhnyak

DOI:

https://doi.org/10.11603/24116-4944.2016.1.5978

Keywords:

newborn, the cardiovascular system, free radical oxidation, antioxidant defense system.

Abstract

The article analyzes the results of a study of indicators of free
radical oxidation and antioxidant defense system in newborns with impaired function of the cardiovascular system in conditions of
pathological birth stress. Determination of these systems will help to diagnose the antioxidant deficiency at the subcellular level. And
prevent its consequences, which are dysfunction of the organ systems in the conditions of hypoxia in the perinatal pathology.

References

Bezkaravaynyy B. A. Osobennosty serdechnoho rytma u nedonoshennykh novorozhdennykh s perynatalʹnym porazhenyem tsentralʹnoy nervnoy systemy / B. A. Bezkaravaynyy, H. A. Solovʹeva // Zdorovʹe rebenka. – 2010. – № 3. – S. 116–119.

Posthypoksycheskaya yshemyya myokarda u novorozhdennykh detey: dyahnostyka y terapyya tyazhelykh form / YU. N. Belova,

A. A. Tarasova, V. N. Podkopaev, Y. F. Ostreykov // Anestezyolohyya y reanymatolohyya. – 2012. – № 1. – S. 65–68.

Osobennosty perekysnoho okyslenyya lypydov y antyoksydantnoy aktyvnosty u detey ranneho vozrasta s zaderzhkoy nervno-psykhycheskoho razvytyya y perynatalʹnoho porazhenyya TSNS v anamneze / E. A. Vorobʹeva, N. V. Dolotova, O. YU. Kocherova [y dr.] // Vestnyk novykh medytsynskykh tekhnolohyy. – 2011. – t. 18, № 1. – S.49–51.

Kolishetsʹka M. A. Rolʹ porushenʹ protsesiv perekysnoho okyslennya lipidiv ta antyoksydantnoho zakhystu v bronkhakh morsʹkykh svynok u ranniy period formuvannya eksperymentalʹnoyi bronkhialʹnoyi astmy / M. A. Kolishetsʹka // Visnyk problem biolohiyi i medytsyny. – 2013. – T. 1 (104), vyp. 4. –S. 143–146.

Kudryavtseva YU. V. Kataraktohenez y starenye khrustalyka: korrektsyya narushenyy : avtoref. dys. na soyskanye uchen. stepeny d-ra med. nauk / YU. V. Kudryavtseva. – N. Novhorod,2015. – 20 s.

Lashyna N. B. Dyfferentsyalʹnaya dyahnostyka porazhenyy myokarda ynfektsyonnoho y hypoksycheskoho heneza u novorozhdennykh detey (obzor lyteratury) / N. B. Lashyna // Med. panorama. – 2010. – № 8. – S. 23–28.

Lashyna N. B. Kompleksnaya otsenka sostoyanyya myokarda u donoshennykh novorozhdennykh pry planovom abdomynalʹnom rodorazreshenyy : avtoref. dys. na soyskanye uchen. stepeny kand. med. nauk / N. B. Lashyna. – Mynsk, 2014. – 24 s.

Lytvytskyy P. F. Klynycheskaya patofyzyolohyya /P. F. Lytvytskyy. – M. : Praktycheskaya medytsyna, 2015. – 776 s.

Loboda A. N. Soderzhanye g-hlutamyltranspeptydazy v syvorotke krovy y moche u novorozhdennykh kak pokazatelʹ narushenyya funktsyy pochek vsledstvye asfyksyy / A. N. Loboda, V. É. Markevych // Klynycheskaya medytsyna. – 2014. – t. 6, № 4. – S. 102–107.

Manishchenkova YU. O. Okyslyuvalʹna modyfikatsiya bilkiv u khvorykh z komorbidnoyu patolohiyeyu / YU. O. Manishchenkova, O. A. Orlova, L. V. Shkala // Ukrayinsʹkyy zhurnal ekstremalʹnoyi medytsyny imeni H. O. Mozhayeva. – 2010. – t. 11,№ 1. – S. 119–122.

Markevych V. E. Antyoksydantnyy zakhyst nedonoshenykh novonarodzhenykh u razi hipoksychno-ishemichnoho urazhennya tsentralʹnoyi nervovoyi systemy / V. E. Markevych, I. V. Tarasova, V. O. Petrashenko // Zdorovʹe rebenka. – 2011. – № 2 (29). – S. 107–110.

Nahornaya N. V. Oksydatyvnyy stress: vlyyanye na orhanyzm cheloveka, metody otsenky / N. V. Nahornaya, N. A. Chetveryk // Zdorovʹe rebenka. – 2010. – № 2(23). –S. 140–145.

Netyukhaylo L. H. Aktyvni formy kysnyu (ohlyad literatury) / L. H. Netyukhaylo, S. V. Kharchenko // Young Scientist.– 2014. – № 9 (12). – S. 131–135.

Aktyvnostʹ fermentov systemy hlutatyona v pochkakh krys pry chrezmernykh fyzycheskykh nahruzkakh [Élektronnyy resurs] / E. A. Chyhrynskyy, V. D. Konvay, E. S. Efremenko, M. Y. Sosnyn // Sovremennye problemy nauky y obrazovanyya. – 2014. – № 4. – Rezhym dostupa k resursu : http://www. science-education.ru/ru/article/view?id=13884.

Damian Hutter, John Kingdom, and Edgar Jaeggi. Causes and Mechanisms of Intrauterine Hypoxia and Its Impact on the Fetal Cardiovascular System: A Review [elektronnyy resurs]/ International Journal of Pediatrics, 2010, Article ID 401323, 9 pages.doi:10.1155/2010/401323. Available from: http://www.hindawi.com/journals/ijpedi/2010/401323/

Developmental Programming of Cardiovascular Dysfunction by Prenatal Hypoxia and Oxidative Stress/ A. Dino Giussani, Emily J. Camm, Youguo Niu [et al.] // PLoS ONE. – 2012. – Vol. 7(2). e31017. doi:10.1371/journal.pone.0031017

Eloisa Gitto, Gabriella DʺAngelo, Erika Cusumano and Russel J. Reiter (2012). Oxidative Stress of Newborn, Complementary Pediatrics, Dr. Öner Özdemir (Ed.), ISBN: 978- 953-51-0155-0, InTech, DOI: 10.5772/32062.

Emily R. Pfeiffer, Jared R. Tangney, Jeffrey H. Omens, and Andrew D. McCulloch. Biomechanics of Cardiac Electromechanical Coupling and Mechanoelectric Feedback/ Journal of Biomechanical Engineering. 2014; Vol. 136: 0210071 – 02100711

Gregg L. Semenza. Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology / L. Gregg Semenza // Pathology: Mechanisms of Disease. – 2014. – Vol. 9. R. 47–71.

Effect of therapeutic hypothermia on oxidative stress and outcome in term neonates with perinatal asphyxia: a randomized controlled trial / R. Joy, F. Pournami, A. Bethou // J. Trop Pediatr. – 2013. – Vol. 59(1). – P. 17–22, doi.org/10.1093/ tropej/fms036

Free radicals, antioxidants and functional foods: Impact on human health / V. Lobo, A. Patil, A. Phatak, N. Chandra // Pharmacogn. Rev. – 2010. – Vol. 4(8). – P. 118–126.

Published

2016-04-04

How to Cite

Hodovanets, Y. D., & Peryzhnyak, A. I. (2016). ANTIOXIDANT DEFENSE SYSTEM OF THE NEWBORNS’ ORGANISM WITH FUNCTIONAL CARDIOVASCULAR SYSTEM DISORDER ON THE BACKGROUND PERYNATAL PATHOLOGY. Actual Problems of Pediatrics, Obstetrics and Gynecology, (1). https://doi.org/10.11603/24116-4944.2016.1.5978

Issue

Section

PEDIATRICS