FERTILITY PROBLEMS IN WOMEN OF OLDER REPRODUCTIVE AGE (LITERATURE REVIEW).

Authors

  • I. V. Korda
  • S. V. Khmil
  • A. S. Khmil

DOI:

https://doi.org/10.11603/24116-4944.2015.2.4790

Keywords:

fertility, older reproductive age, ART.

Abstract

With age female fertility significantly reduces mainly by reducing the number and quality of oocytes. Endocrine function of ovaries also undergoes influence of age and is unable to maintain neuroendocrine regulation. Perhaps the age-related changes begin primarily in the hypothalamic-pituitary area, but it needs further research. Age-related changes occur in the tissues of the uterus, especially the endometrium, which is unable to provide adequate support for the development and implantation of the embryo.

Author Biography

I. V. Korda

.

References

Baev O. R. Fetoplatsentarnaya nedostatochnostʹ u pervorodyashchykh starshe ZO let: faktory ryska; osobennosty techenyya beremennosty, rodov y perynatalʹnykh yskhodov / O. R. Baev, V. S. Belousova / / Materyaly VIII Rossyyskoho foruma «Matʹ y dytya».- M., 2OO6. - S. 26-27.

American Society for Reproductive Medicine (ASRM). Age and Fertility a Guide for Patients, Birmingham, AL. - 2OOZ. - P. 7-9.

Fitzgerald S. Aging and reproductive potential in women / C. Fitzgerald, A. E. Zimon, E. E. Jones / / Yale J.Biol. Med. - 1998. - Vol. 71 (5). - P. Z67-Z81.

Gindoff P. R. Reproductive potential in the older woman / P. R. Gindoff, R. Jewelewicz / / Fertil. Steril. - 1986. - Vol. 46 (6). - P. 989-1OO1.

http://www.unian.ua/society/7998O1 -v-ukrajinividsotok- rozluchen-syagnuv-61 .html

Informatsiyno-statystychnyy dovidnyk pro dopomizhni reproduktyvni tekhnolohiyi v Ukrayini. - K. : MOZ Ukrayiny, 2O11.

Dopomizhni reproduktyvni tekhnolohiyi likuvannya bezpliddya : navch. posib. / za zah. red. F. V. Dakhno, V. V. Kaminsʹkoho, O. M. Yuzʹko. - K., 2O11. - ZZ4 s.

Dopomizhni reproduktyvni tekhnolohiyi v Ukrayini / O. M. Yuzʹko, V. V. Kaminsʹkyy, N. YA. Zhylka [ta in.] / /Zb. nauk. pratsʹ spivrob. NMAPO im. P. L. Shupyka. - K., 2OO8. - Vyp. 17, kn. 4. - S. 5-14.

Kocourkova J. Demographic relevancy of increased use of assisted reproduction in European countries / J. Kocourkova, B. Burcin, T. Kucera / / ReprodHealth. - 2O14. - Vol. 26. - P. 11-Z7. doi: 1O.1186/1742-4755-11-Z7.

www.cdc.gov/reproductive h e a lth /In fe rtility / Index.htm

Johnson J. A. Delayed child-bearing / J. A. Johnson, S. Tough; Society of Obstetricians and Gynaecologists of Canada / / J. Obstet. Gynaecol. Can. - 2O12. - Vol. Z4 (1). - P. 8O-9Z.

Reduced quality and accelerated follicle loss with female reproductive aging - does decline in theca dehydroepiandrosterone (DHEA) underlie the problem? / / J. Biomed. Sci. - 2O1Z. - Vol. 1Z. - P. 2O-9Z. doi: 1O.1186/142Z-O127-2O-9Z.

Yuzʹko O. M. Otsinka ovarialʹnoho rezervu u zhinok iz bezpliddyam / O. M. Yuzʹko, P. O. Halayko / / Zdorovʹe zhenshchyny. - 2OO8. - № 4. - S. 168-169.

Boyarskyy K. YU. Klynycheskoe znachenye testov opredelenyya ovaryalʹnoho rezerva v lechenyy besplodyya : avtoref. dys. kand. med. nauk / K. YU. Boyarskyy. - SPb., 2OOO. - 26 s.

Dopomizhni reproduktyvni tekhnolohiyi v Ukrayini / O. M. Yuzʹko, N. YA. Zhylka [ta in.] / / Zhinochyy likar. -2OO7. - № Z (11). - S. 8-12.

Ivanyuta L. I. Poetapna diahnostyka ta likuvannya bezplidnosti v shlyubi / L. I. Ivanyuta, S. O. Ivanyuta / / Nova medytsyna. - 2OO2. - № 4. - S. 28-ZO.

Kulakov V. Y. Ékstrakorporalʹnoe oplodotvorenye y eho novoe napravlenye v lechenyy zhenskoho y muzhskoho besplodyya / V. Y. Kulakov, B. V. Leonov. - M. : Med. ynform. ahent•stvo, 2OO2. - 782 s.

Apoptosis of germ cells during human prenatal oogenesis / A. De Pol, F. Vaccina, A. Forabosco [et al.] / / Hum. Reprod. - 1997. - Vol. 12 (1O). - P. 2235-2241. [PubMed]

Richardson S. J. Follicular depletion during the menopausal transition: evidence for accelerated loss and ultimate exhaustion / S. J. Richardson, V. Senikas, J. F. Nelson / / J. Clin. Endocrinol. Metab. - 1987. - Vol. 65 (6). - P. 1231-1237. [PubMed]

Faddy M. J. A model conforming the decline in follicle numbers to the age of menopause in women / M. J. Faddy, R. G. Gosden / / Hum. Reprod. - 1996. - Vol. 11 (7). - P. 1484-1486. [PubMed]

Follicular volume and number during in-vitro fertilization: association with oocyte developmental capacity and pregnancy rate / A. M. Arnot, P. Vandekerckhove, M. A. DeBono, A. J. Rutherford / / Hum. Reprod. - 1995. - Vol. 1O (2). - P. 256-261. [PubMed]

Faddy M. J. A model confirming the decline in follicle numbers to the age of menopause in women / M. J. Faddy, R. G. Gosden. / / Hum. Reprod. - 1996. - Vol. 11. - P. 1484-1486.

Age and the ovarian follicle pool assessed with transvaginal ltrasonography / M. L. Reuss, J. Kline, R. Santos [et al.] / / Am. J. Obstet. Gynecol. - 1996. - Vol. 174. - P. 6247.

The impact ofthe women's age on the success of standard and donor in vitro fertilization / A. M. Stolwijk, G. A. Zielhuis, M. V. Sauer [et al.] / / Fertil. Steril. - 1997. - Vol. 67. - P. 7O2-71O.

Poor oocyte quality rather than implantation failure as a cause of age-related decline in female fertility / D. Navot, P. A. Bergh, M. A. Williams [et al] / / Lancet. - 1991. - Vol. 337. - P. 1375-1377.

Sauer M. V. Pregnancy wastage and reproductive aging: the oocyte donation model /M. V. Sauer / / Current Opin. Obstet. Gynecol. - 1996. - Vol. 8. - P. 226-229.analysis of mechanisms of meiotic dysfunction and anaphase lagging in primary oocytes / S. Sugawara, K. Mikamo / / Cytogenet. Cell. Genet. - 1980. - Vol. 20. - P. 251-255.

Hansman I. Altered nuclear progression precedes nondisjunction in oocytes / I. Hansman, F. Theurig / / 7th Int. Congr. Hum. Genet. - Berlin, 1986. - P. 150.

Does the karyotype of a spontaneous abortion predict the karyotype of a subsequent abortion? Evidence from 273 women with two karyotyped spontaneous abortions / D. Warburton, J. Kline, Z. Stein [et al.] / / Am. J. Hum. Genetics. - 1987. - Vol. 41. - P. 465-483.

Results of in vitro fertilization attempts in women 40 years of age and older: the Norfolk experience / A. Romeu, S. J. Muasher, A. A. Acosta [et al.] / / Fertil. Steril. - 1987. - Vol. 47. - P. 130-136.

Lim A. S. Age-related decline in fertility: a link to degenerative oocytes? / A. S. Lim, M. F. Tsakok / / Fertil. Steril. - 1997. - Vol. 68. - P. 265-271.

The age-related decline in female fecundity: a quantitative controlled study of implanting capacity and survival of individual embryos after in vitro fertilization / M. G. R. Hull, C. F. Fleming, A. O. Hughes, A. McDermott / / Fertil. Steril. - 1996. - Vol. 65. - P. 783-790.

Abnormal chromosome behavior in human oocytes which remained unfertilized during in vitro fertilization / H. Spielmann, C. Kruber, M. Stauber, R. J. Vogel / / In Vitro Fert.Embryo Transfer. - 1985. - Vol. 2. - P. 138242.

Lim A. S. Age-related decline in fertility: a link to degenerative oocytes? / A. S. Lim, M. F. Tsakok / / Fertil. Steril. - 1997. - Vol. 68. - P. 265-271.

Pellestor F. Frequency and distribution of aneuploidy in human female gametes / F. Pellestor / / Hum. Genet. - 1991. - Vol. 86. - P. 283-288.

Sherman B. M. The menopausal transition: Analysis of LH, FSH oestradiol and progesterone concentrations during menstrual cycles of older women / B. M. Sherman, J. H. West, S. G. Korenman / / J. Clin. Endocrinol. Metab. - 1976. - Vol. 42. - P. 629-636.

Occult ovarian failure: A syndrome of infertility, regular menses and elevated follicle stimulating hormone concentrations / I. T. Cameron, F. C. O'Shea, J. M. Rolland [et al.] / / J. Clin. Endocrinol. Metab. - 1988. - Vol. 67. - P. 1190-1194.

Flood J. T. The occult ovarian factor in unexplained infertility / J. T. Flood, R. T. Scott, R. G. Brzyski //Abstracts Am. Coll. Obstet. Gynecol. Ann. Meeting. - 1989. - P. 22.

Progressive changes in LH and FSH and the LH:FSH ratio in women throughout reproductive life / E. A. Lenton, L. Sexton, S. J. Lee, I. D. Cooke / / Maturitas. - 1988. - Vol. 10. - P. 35-43.

Sherman B. M. The menopausal transition: Analysis of LH, FSH oestradiol and progesterone concentrations during menstrual cycles of older women / B. M. Sherman, J. H. West, S. G. Korenman / / J. Clin. Endocrinol. Metab. - 1976. - Vol. 42. - P. 629-636.

The effect of age on the cyclical patterns of plasma LH, FSH oestradiol and progesterone in women with regular menstrual cycles / S. J. Lee, E. A. Lenton, L. Sexton, I. D. Cooke / / Hum. Reprod. - 1988. - Vol. 3. - P. 851-855.

Richardson S. J. Follicular depletion during the menopausal transition:Evidence for accelerated loss and ultimate exhaustion / S. J. Richardson, V. Senikas, J. F. Nelson / / J. Clin. Endocrinol. Metab. - 1987. - Vol. 65. - P. 1231-1237.

Role of estradiol in the rise in follicle stimulating hormone levels during the luteal-follicular transition / E. Le Nestour, J. Marraoui, N. Lahlou [et al.] / / J. Clin. Endocrinol. Metab. - 1993. - Vol. 77. - P. 439-442.

Rosenwaks Z. The role of maternal age in assisted reproduction / Z. Rosenwaks, O. W. Davis, M. A. Damario // Hum. Reprod. - 1995. - Vol. 10. - P. 165-173.

Circulating immunoreactive inhibin levels during the normal menstrual cycle / R. I. McLaghlan, D. M. Robertson, D. L. Healy [et al.] / / J. Clin. Endocrinol. Metab. - 1987. - Vol. 65. - P. 954-961.

Dynamic changes in circulating inhibin levels during the luteal-follicular transition of the human menstrual cycle / S. I. Roseff, M. L. Bangah, L. M. Kettel, [et al.] / / J. Clin. Endocrinol. Metab. - 1989. - Vol. 69. - P. 1033-1039.

Gonadotrophin, steroid and inhibin levels in women with incipient ovarian failure during anovulatory and ovulatory rebound cycles / H. M. Buckler, C. A. Evans, H. Mamtora [et al.] / / J Clin. Endocrinol. Metab. - 1991. - Vol. 72. - P. 116-124.

Effects of aging on the human ovary: the secretion of immunoreactive alpha-inhibin and progesterone / A. Pellicier, C. Simon, M. Mari [et al.] / / Fertil. Steril. - 1994. - Vol. 61. - P. 663-668.

Kiyoshi Shimizu. Relationship of decrease in fecundity with advancing age to structural changes in mouse endometrium / Kiyoshi Shimizu, Jinzo Yamada / / J. Anat. - 2000. - Vol. 196(Pt 1). - P. 111-114.

Niklaus A. L. 1. Characteristics of the uterine luminal surface epithelium at preovulatory and preimplantation stages in the marmoset monkey / A. L. 1. Niklaus, C. R. Murphy, A. Lopata / / Anat. Rec. - 2001. - Vol. 1;264(1). P. 82-92.

Niklaus A. L. Ultrastructural studies of glycan changes in the apical surface of the uterine epithelium during pre-ovulatory and and pre-implantation stages in the marmoset monkey / A. L. Niklaus, C. R. Murphy, A. Lopata / / Anat. Rec. - 1999. - Vol. 255 (3). - P. 241251.

Craig S. S. Age changes in density of endometrial stromal cells of the rat / S. S. Craig, W. P. Jollie / / Exp. Gerontol. - 1985. - Vol. 20 (2). - P. 93-97.

Published

2015-07-13

How to Cite

Korda, I. V., Khmil, S. V., & Khmil, A. S. (2015). FERTILITY PROBLEMS IN WOMEN OF OLDER REPRODUCTIVE AGE (LITERATURE REVIEW). Actual Problems of Pediatrics, Obstetrics and Gynecology, (2). https://doi.org/10.11603/24116-4944.2015.2.4790

Issue

Section

OBSTETRICS AND GYNECOLOGY