CHANGES IN MINERAL AND РТОТЕ^ EXCHANGE IN РREGNANTS WITH ARTERIAL HYРOTENSION AS A RISK FACTOR FOR DEVELOРMENT OF DENTAL CARIES IN CHILDREN.
DOI:
https://doi.org/10.11603/24116-4944.2015.1.4714Keywords:
arterial hypotension, pregnancy, mineral and protein exchange, children, caries.Abstract
There are mixed and conflicting reports in the literature about the impact of arterial hypotension (AH) on the fetus and newborn, therefore, investigation done by us is actual. Mineral and protein exchange has been studied in 70 pregnants with AH and in 50 women with normal blood pressure at 16-24 and 32-40 weeks of pregnancy, and also teeth affection by caries in 80 children from mothers with AH has been studied. Control group included 50 children from mothers with physiological pregnancy. It was shown, that on the background of AH in pregnancy there is a significant increase in serum potassium, calcium, slight increase of magnesium, essential decrease in sodium and small - in phosphorus. Simultaneously in pregnant women with AH decrease of microelements' indicators (copper, manganese, zinc, cobalt) is observed. Elevated calcium levels in the blood of pregnant women with AH can be considered as the risk of osteoporosis development in postnatal period. Study of protein exchange in pregnant women with AH showed increase in total protein (Р<0.05) increase in the number of albumins (Р<0.05), decrease in a1-globulins (Р<0.001), decrease in y-globulins (Р>0.05), an increase of a2-globulins (Р<0.05) and в-globulins (Р>0.05). Reduction of y-globulins fraction on the background of increased amounts of total protein is a risk factor of immune processes reduction in pregnant women with AH. The caries prevalence of milk and permanent teeth in children born from mothers with AH is 95.7 %, which is significantly higher than in children born from mothers with physiological pregnancy (72.7 %).
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