ENDOTHELIAL DYSFUNCTION AS A DIAGNOSTIC AND PROGNOSIS CRITERION OF HEMORRHAGIC VASCULITIS COURSE IN CHILDREN.
DOI:
https://doi.org/10.11603/24116-4944.2015.1.4673Keywords:
amsterdam dwarfism, Cornelia de Lange syndrome, children.Abstract
The hemorrhagic vasculitis is from the group of systemic vasculitis and seen as a generalized microthrombovasculitis. The disease is one of the actual pediatrics problems, which is due to diagnosis difficulties in the early stages. The purpose of the study was to determine the endothelial function status in children with hemorrhagic vasculitis. The relation between of hemostatic disorders and process activity was determined. The endothelial dysfunction is presence in all children with hemorrhagic vasculitis. The correlation between circulating immune complexes levels, indexes of T- and B-lymphocytes and the disease severity was detected. The using possibility of minimally invasive ultrasonic methods for determining the endothelial function state was proved.
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